Near‐Infrared Light‐Activatable Dual‐Action Nanoparticle Combats the Established Biofilms of Methicillin‐Resistant Staphylococcus aureus and Its Accompanying …

Z Yuan, C Lin, L Dai, Y He, J Hu, K Xu, B Tao, P Liu… - Small, 2021 - Wiley Online Library
Clinically, inhibition of both bacterial infection and excessive inflammation is a crucial step
for improved wound treatments. Herein, the fabrication of near‐infrared‐light (NIR) …

Emerging delivery strategies of carbon monoxide for therapeutic applications: from CO gas to CO releasing nanomaterials

H Yan, J Du, S Zhu, G Nie, H Zhang, Z Gu, Y Zhao - Small, 2019 - Wiley Online Library
Carbon monoxide (CO) therapy has emerged as a hot topic under exploration in the field of
gas therapy as it shows the promise of treating various diseases. Due to the gaseous …

[HTML][HTML] Ruthenium complexes in the fight against pathogenic microorganisms. An extensive review

AC Munteanu, V Uivarosi - Pharmaceutics, 2021 - mdpi.com
The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

Type-I Photosensitizer-Triggered Controllable Carbon Monoxide Release for Effective Treatment of Staph Skin Infection

L Cao, X Lin, X Liu, M Wu, S Liu, T Wang, D Mao… - Nano Letters, 2023 - ACS Publications
Staphylococcus aureus (S. aureus) infection is a major infectious skin disease that is highly
resistant to conventional antibiotic treatment and host immune defense, leading to …

[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3

HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …

CORM‐3 Attenuates Oxidative Stress‐Induced Bone Loss via the Nrf2/HO‐1 Pathway

C Jin, B Lin, G Zheng, K Tan, G Liu… - Oxidative Medicine …, 2022 - Wiley Online Library
Bone metabolism occurs in the entire life of an individual and is required for maintaining
skeletal homeostasis. The imbalance between osteogenesis and osteoclastogenesis …

The microbiology of ruthenium complexes

HM Southam, JA Butler, JA Chapman… - Advances in microbial …, 2017 - Elsevier
Ruthenium is seldom mentioned in microbiology texts, due to the fact that this metal has no
known, essential roles in biological systems, nor is it generally considered toxic. Since the …

[HTML][HTML] CO-releasing metal carbonyl compounds as antimicrobial agents in the post-antibiotic era

LK Wareham, RK Poole, M Tinajero-Trejo - Journal of Biological Chemistry, 2015 - ASBMB
The possibility of a" post-antibiotic era" in the 21st century, in which common infections may
kill, has prompted research into radically new antimicrobials. CO-releasing molecules …

Ruthenium (II) carbon monoxide releasing molecules: Structural perspective, antimicrobial and anti-inflammatory properties

AM Mansour, RM Khaled, E Khaled, SK Ahmed… - Biochemical …, 2022 - Elsevier
Carbon monoxide has recently emerged to promote tissue regeneration, enhance the innate
immune system, and have anti-inflammatory and antibacterial properties. While the first …

Bioinorganic systems responsive to the diatomic gases O2, NO, and CO: From biological sensors to therapy

LG de Franca Lopes, FSG Júnior, AKM Holanda… - Coordination Chemistry …, 2021 - Elsevier
The diatomic molecules, O 2, NO and CO, have had a myriad of roles in biology. Due to this,
nature has developed many sensing proteins to perceive and respond to changes in the …