Branched chain amino acids: beyond nutrition metabolism

C Nie, T He, W Zhang, G Zhang, X Ma - International journal of molecular …, 2018 - mdpi.com
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …

Novel metabolic and physiological functions of branched chain amino acids: a review

S Zhang, X Zeng, M Ren, X Mao, S Qiao - Journal of animal science and …, 2017 - Springer
It is widely known that branched chain amino acids (BCAA) are not only elementary
components for building muscle tissue but also participate in increasing protein synthesis in …

Cardiac metabolism and its interactions with contraction, growth, and survival of cardiomyocytes

SC Kolwicz Jr, S Purohit, R Tian - Circulation research, 2013 - Am Heart Assoc
The network for cardiac fuel metabolism contains intricate sets of interacting pathways that
result in both ATP-producing and non–ATP-producing end points for each class of energy …

How much protein can the body use in a single meal for muscle-building? Implications for daily protein distribution

BJ Schoenfeld, AA Aragon - Journal of the International Society of Sports …, 2018 - Springer
Controversy exists about the maximum amount of protein that can be utilized for lean tissue-
building purposes in a single meal for those involved in regimented resistance training. It …

Protein consumption and the elderly: what is the optimal level of intake?

JI Baum, IY Kim, RR Wolfe - Nutrients, 2016 - mdpi.com
Maintaining independence, quality of life, and health is crucial for elderly adults. One of the
major threats to living independently is the loss of muscle mass, strength, and function that …

Muscle atrophy induced by mechanical unloading: mechanisms and potential countermeasures

Y Gao, Y Arfat, H Wang, N Goswami - Frontiers in physiology, 2018 - frontiersin.org
Prolonged periods of skeletal muscle inactivity or mechanical unloading (bed rest, hindlimb
unloading, immobilization, spaceflight and reduced step) can result in a significant loss of …

Effects of leucine and its metabolite β‐hydroxy‐β‐methylbutyrate on human skeletal muscle protein metabolism

DJ Wilkinson, T Hossain, DS Hill… - The Journal of …, 2013 - Wiley Online Library
Key points• The branched‐chain amino acid (BCAA) leucine acts as both a 'trigger'for the
initiation of protein synthesis, and as a substrate for newly synthesized protein.• As a BCAA …

The role of leucine and its metabolites in protein and energy metabolism

Y Duan, F Li, Y Li, Y Tang, X Kong, Z Feng, TG Anthony… - Amino acids, 2016 - Springer
Leucine (Leu) is a nutritionally essential branched-chain amino acid (BCAA) in animal
nutrition. It is usually one of the most abundant amino acids in high-quality protein foods …

[HTML][HTML] Branched-chain amino acid ingestion stimulates muscle myofibrillar protein synthesis following resistance exercise in humans

SR Jackman, OC Witard, A Philp, GA Wallis… - Frontiers in …, 2017 - frontiersin.org
The ingestion of intact protein or essential amino acids (EAA) stimulates mechanistic target
of rapamycin complex-1 (mTORC1) signaling and muscle protein synthesis (MPS) following …

Factors mediating spaceflight-induced skeletal muscle atrophy

PHU Lee, M Chung, Z Ren… - American Journal of …, 2022 - journals.physiology.org
Skeletal muscle atrophy is a well-known consequence of spaceflight. Because of the
potential significant impact of muscle atrophy and muscle dysfunction on astronauts and …