Metastasis follows the inappropriate activation of a genetic programme termed invasive
growth, which is a physiological process that occurs during embryonic development and …

Proper response of normal stem cells (NSC) to motomorphogens and chemoattractants
plays a pivotal role in organ development and renewal/regeneration of damaged tissues …

By employing multiparameter sorting, we identified in murine bone marrow (BM) a
homogenous population of rare (∼ 0.02% of BMMNC) Sca-1+ lin− CD45− cells that express …

Recently, we purified from adult murine bone marrow (BM) a population of CXCR4+, Oct-4+
SSEA-1+, Sca-1+ lin− CD45− very small embryonic-like (VSEL) stem cells and hypothesized …

Accumulating laboratory studies have implicated the mobilization of bone marrow (BM)-
derived stem cells in brain plasticity and stroke therapy. This mobilization of bone cells to the …

Recent results have shown the ability of bone marrow cells to migrate in the brain and to
acquire neuronal or glial characteristics. In vitro, bone marrow‐derived MSCs can be …

Heart failure carries a poor prognosis with few treatment options. While myocardial stem cell
therapeutic trials have traditionally relied on intracoronary infusion or intramyocardial …

Accumulating evidence demonstrates that adult tissues contain a population of stem cells
that express early developmental markers such as stage-specific embryonic antigen and …

Background and Purpose—In a murine model of stroke, we identified a population of very
small embryonic-like (VSEL) stem cells (SCs) in adult murine bone marrow that could be …

Background There has been increasing interest recently in the plasticity of mesenchymal
stem cells (MSCs) and their potential to differentiate into neural lineages. To unravel the …