At the nexus of antibiotics and metals: the impact of Cu and Zn on antibiotic activity and resistance

K Poole - Trends in microbiology, 2017 - cell.com
Environmental influences on antibiotic activity and resistance can wreak havoc with in vivo
antibiotic efficacy and, ultimately, antimicrobial chemotherapy. In nature, bacteria encounter …

[HTML][HTML] Repositioning of fluoroquinolones from antibiotic to anti-cancer agents: An underestimated truth

V Yadav, P Talwar - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Increasing development costs and higher failure rate in clinical trials has reduced the
repertoire of newer drugs in the market for clinical use. The most appropriate approach to …

Iron and zinc ions, potent weapons against multidrug-resistant bacteria

Q Ye, W Chen, H Huang, Y Tang, W Wang… - Applied Microbiology …, 2020 - Springer
Drug-resistant bacteria are becoming an increasingly widespread problem in the clinical
setting. The current pipeline of antibiotics cannot provide satisfactory options for clinicians …

Fluoroquinolones metal complexation and its environmental impacts

A Cuprys, R Pulicharla, SK Brar, P Drogui… - Coordination Chemistry …, 2018 - Elsevier
Fluoroquinolones (FQs), the group of broad spectrum antimicrobials, are frequently detected
in different environmental compartments, mostly due to incomplete metabolism in the target …

Cyclic voltammetric DNA binding investigations on some anticancer potential metal complexes: a review

N Arshad, SI Farooqi - Applied biochemistry and biotechnology, 2018 - Springer
Cancer is developed by rapid, uncontrolled, and abnormal cell proliferation and one of the
leading causes of deaths worldwide in human beings. For the remedial measures of …

Grandivittin as a natural minor groove binder extracted from Ferulago macrocarpa to ct-DNA, experimental and in silico analysis

F Ahmadi, S Valadbeigi, SE Sajjadi… - Chemico-biological …, 2016 - Elsevier
Abstract Ferulago macrocarpa (Fenzl) Boiss., is an endemic medicinal herb of Iran. In this
study a dihydrofuranocoumarin called grandivittin (GRA) was separate and purified from …

Interaction of bioessential metal ions with quinolone antibiotics: Structural features and biological evaluation

NV Nedeljković, MV Nikolić, MŽ Mijajlović… - Inorganica Chimica …, 2021 - Elsevier
Bioessential metal complexes with quinolone antibiotics as ligands attract wide attention in
bioinorganic chemistry due to their greater biological potential that may lead to the synthesis …

Highly efficient and antibacterial zinc norfloxacin thermal stabilizer for poly (vinyl chloride)

Y Shi, S Chen, M Ma, B Wu, J Ying, X Xu, X Wang - RSC advances, 2016 - pubs.rsc.org
A novel kind of highly efficient and antibacterial thermal stabilizer, zinc norfloxacin (Zn
(C16H17FN3O3) 2· 4H2O, represented as ZnNo2), for poly (vinyl chloride)(PVC) was first …

Proposed model for binding of permethrin and deltamethrin insecticides with ct-DNA, a structural comparative study

F Ahmadi, K Ghanbari - Ecotoxicology and environmental safety, 2014 - Elsevier
In this work, the interaction of two synthetic pyrethroid insecticides, permethrin (PER) and
deltamethrin (DEL), with ct-DNA has been studied by cyclic voltammetry (CV), circular …

Thermal, spectroscopic and antimicrobial activity characterization of some norfloxacin complexes

WDG Nunes, ALCS do Nascimento, A Moura… - Journal of Thermal …, 2018 - Springer
Coordination compounds of transition metals with norfloxacin (Nor) have potential to
improve its effectiveness, as already discussed for some compounds found in the literature …