Process calculi for biological processes

A Bernini, L Brodo, P Degano, M Falaschi, D Hermith - Natural Computing, 2018 - Springer
Abstract Systems biology is a research area devoted to developing computational
frameworks for modeling biological systems in a holistic fashion. Within this approach, the …

Abstracting the differential semantics of rule-based models: exact and automated model reduction

V Danos, J Feret, W Fontana… - 2010 25th Annual …, 2010 - ieeexplore.ieee.org
Rule-based approaches (as in our own Kappa, or the BNG language, or many other
propositions allowing the consideration of" reaction classes'') offer new and more powerful …

[HTML][HTML] A proof theoretic view of spatial and temporal dependencies in biochemical systems

C Olarte, D Chiarugi, M Falaschi, D Hermith - Theoretical Computer Science, 2016 - Elsevier
The behavior of biochemical systems such as metabolic and signaling pathways may
depend on either the location of the reactants or on the time needed for a reaction to occur …

[HTML][HTML] Causal static analysis for brane calculi

C Bodei, R Gori, F Levi - Theoretical Computer Science, 2015 - Elsevier
We present here a static analysis, based on Abstract Interpretation [8], obtained by defining
an abstract version of the causal semantics for the Mate/Bud/Drip (MBD) version of Brane …

Abstract interpretation based verification of temporal properties for bioambients

R Gori, F Levi - Information and Computation, 2010 - Elsevier
This paper concerns the application of formal methods to biological systems, modeled
specifically in BioAmbients, a variant of the Mobile Ambients calculus. Following the …

[HTML][HTML] A static analysis for Brane Calculi providing global occurrence counting information

C Bodei, L Brodo, R Gori, F Levi, A Bernini… - Theoretical Computer …, 2017 - Elsevier
In this paper we propose a static analysis for Brane Calculi [1], based on Abstract
Interpretation [2] techniques. Our analysis statically approximates the dynamic behaviour of …

An analysis for causal properties of membrane interactions

C Bodei, R Gori, F Levi - Electronic Notes in Theoretical Computer Science, 2013 - Elsevier
We present here an analysis, based on Abstract Interpretation [P. Cousot and R. Cousot.
Abstract Interpretation: A Unified Lattice Model for Static Analysis of Programs by …

Accessible Pattern Analyses in Kappa Models

J FERET - Symbolic Approaches to Modeling and Analysis of …, 2023 - books.google.com
Describing and analyzing the large-scale and highly combinatorial systems that arise from
certain mechanistic models in systems biology is still beyond the reach of recent …

Approximating probabilistic behaviors of biological systems using abstract interpretation

A Coletta, R Gori, F Levi - Electronic Notes in Theoretical Computer Science, 2009 - Elsevier
In this paper we apply the Abstract Interpretation approach [P. Cousot and R. Cousot.
Abstract Interpretation: A Unified Lattice Model for Static Analysis of Programs by …

Analyse statique et réduction de modèles de voies de signalisation intracellulaire

J Feret - Informatique Mathématique Une photographie en 2023, 2023 - inria.hal.science
Ce chapitre décrit deux applications des méthodes formelles pour Kappa, un langage de
réécriture de graphes à sites utilisé en modélisation de systèmes biologiques. La première …