The diagnostic criteria of menstrual migraine (MM), migraine related to menstruation and
pure menstrual migraine, are placed in the appendix of the International Classification of …

Abstract Purpose of Review The menstrual cycle involves recurrent fluctuations in hormone
levels and temperature via neuroendocrine feedback loops. This paper reviews the impact …

Background erenumab was safe and effective in clinical trials for the prevention of migraine.
However, real-life data are still lacking. Here we report the clinical experience from an Italian …

Background Two‐thirds of patients with migraine without aura (MwoA) complain ictal
cutaneous allodynia (CA), clinical sign of central nociceptive pathway sensitization, and …

Background Several studies have described potential microRNA (miRNA) biomarkers
associated with migraine, but studies are scarcely reproducible primarily due to the …

Migraine is a highly prevalent neurological disorder. Among the risk factors identified,
psychiatric comorbidities, such as depression, seem to play an important role in its onset …

Background: Dynamic mechanical allodynia (DMA) is both a symptom and a central
sensitization sign, yet no standardized method for quantifying the DMA area has been …

Background Cyclic hormonal fluctuations influence migraine incidence and severity.
Previously, we described reduced menstrual cyclicity in estradiol levels and dermal blood …

Background Pilonidal disease begins in puberty when males and females have different sex
hormone expression. We hypothesize that sex differences can lead to clinical differences in …

Chapter 1 introduces the clinical features and epidemiology of migraine and the association
with cardiovascular disease including stroke. The possible mechanisms behind this …