Nanovaccine: An emerging strategy

A Das, N Ali - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Vaccination is so far the most effective way of eradicating infections. Rapidly
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …

Advancements in prophylactic and therapeutic nanovaccines

P Bhardwaj, E Bhatia, S Sharma, N Ahamad… - Acta Biomaterialia, 2020 - Elsevier
Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …

[HTML][HTML] In vitro and ex vivo models in inhalation biopharmaceutical research—advances, challenges and future perspectives

MA Selo, JA Sake, KJ Kim, C Ehrhardt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Oral inhalation results in pulmonary drug targeting and thereby reduces systemic side
effects, making it the preferred means of drug delivery for the treatment of respiratory …

Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines

LO De Serrano, DJ Burkhart - Journal of nanobiotechnology, 2017 - Springer
Vaccinology is one of the most important cornerstones in modern medicine, providing better
quality of life. The human immune system is composed of innate and adaptive immune …

[HTML][HTML] On the path to predicting immune responses in the lung: modeling the pulmonary innate immune system at the air-liquid interface (ALI)

J Graf, M Trautmann-Rodriguez, S Sabnis… - European Journal of …, 2023 - Elsevier
Chronic respiratory diseases and infections are among the largest contributors to death
globally, many of which still have no cure, including chronic obstructive pulmonary disorder …

Human Lung Organoids—A Novel Experimental and Precision Medicine Approach

L Kühl, P Graichen, N von Daacke, A Mende… - Cells, 2023 - mdpi.com
The global burden of respiratory diseases is very high and still on the rise, prompting the
need for accurate models for basic and translational research. Several model systems are …

Role of NKT cells during viral infection and the development of NKT cell-based nanovaccines

MA Khan, A Khan - Vaccines, 2021 - mdpi.com
Natural killer T (NKT) cells, a small population of T cells, are capable of influencing a wide
range of the immune cells, including T cells, B cells, dendritic cells and macrophages. In the …

Natural products against acute respiratory infections: Strategies and lessons learned

J Langeder, U Grienke, Y Chen, J Kirchmair… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance A wide variety of traditional herbal remedies have been
used throughout history for the treatment of symptoms related to acute respiratory infections …

Use of airway epithelial cell culture to unravel the pathogenesis and study treatment in obstructive airway diseases

TCJ Mertens, H Karmouty-Quintana, C Taube… - Pulmonary …, 2017 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are considered as two distinct
obstructive diseases. Both chronic diseases share a component of airway epithelial …

The expressions of TSLP, IL-33, and IL-17A in monocyte derived dendritic cells from asthma and COPD patients are related to epithelial–macrophage interactions

M Paplinska-Goryca, P Misiukiewicz-Stepien… - Cells, 2020 - mdpi.com
Background. The cross-talk between the external and internal environment in the respiratory
tract involves macrophage/dendritic cell (DC) transepithelial network. Epithelium triggers …