Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19
V Craddock, A Mahajan, L Spikes… - Journal of medical …, 2023 - Wiley Online Library
ABSTRACT SARS‐CoV‐2, the causative agent of COVID‐19 disease, has resulted in the
death of millions worldwide since the beginning of the pandemic in December 2019. While …
death of millions worldwide since the beginning of the pandemic in December 2019. While …
Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
Loop between NLRP3 inflammasome and reactive oxygen species
Significance: Inflammasomes are cytosolic multiprotein complexes that mediate innate
immune pathways. Inflammasomes activate inflammatory caspases and regulate …
immune pathways. Inflammasomes activate inflammatory caspases and regulate …
A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection
SA Narayanan, DA Jamison Jr, JW Guarnieri… - European Journal of …, 2024 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and
mortality worldwide. The betacoronavirus continues to evolve with global health implications …
mortality worldwide. The betacoronavirus continues to evolve with global health implications …
Mitochondrial dysfunction in vascular endothelial cells and its role in atherosclerosis
K Qu, F Yan, X Qin, K Zhang, W He, M Dong… - Frontiers in …, 2022 - frontiersin.org
The mitochondria are essential organelles that generate large amounts of ATP via the
electron transport chain (ECT). Mitochondrial dysfunction causes reactive oxygen species …
electron transport chain (ECT). Mitochondrial dysfunction causes reactive oxygen species …
Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID
E Clough, J Inigo, D Chandra, L Chaves… - Journal of Neuroimmune …, 2021 - Springer
Emerging clinical data from the current COVID-19 pandemic suggests that~ 40% of COVID-
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease
Y Yoshimatsu, T Watabe - Inflammation and Regeneration, 2022 - Springer
Abstract Endothelial–mesenchymal transition (EndoMT), a cellular differentiation process in
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …
which endothelial cells (ECs) lose their properties and differentiate into mesenchymal cells …
COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction
E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …
causes acute atypical respiratory symptoms and has led to profound changes in our lives …