The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …

The objective of this study is to examine IL-11-induced mechanisms of inflammatory cell
migration to the central nervous system (CNS). We report that IL-11 is produced at highest …

Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

Ketogenic Diet is a nutritional pattern often used as dietotherapy in inflammatory diseases,
including neurological disorders. Applied on epileptic children since 1920, in recent years it …

The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …

Inflammasomes are multi-protein macromolecular complexes that typically comprise of three
units, a sensor, an adaptor and procaspase-1. The assembly of each inflammasome is …

Multiple sclerosis (MS) is a chronic, autoimmune and neuroinflammatory disease of the
central nervous system (CNS) mediated by autoreactive T cells directed against myelin …

Over the last decade, significant progress has been achieved in defining mechanisms
underlying NLR regulation of immune system function. However, several NLR family …