SERS-activated platforms for immunoassay: probes, encoding methods, and applications
Z Wang, S Zong, L Wu, D Zhu, Y Cui - Chemical reviews, 2017 - ACS Publications
Owing to their excellent multiplexing ability, high sensitivity, and large dynamic range,
immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal …
immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal …
Aging hallmarks and progression and age-related diseases: a landscape view of research advancement
Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …
of cell damage. Continual functional decline in the intrinsic ability of living organisms to …
High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platform
CY Tham, LF Poon, TD Yan, JYP Koh… - Nature …, 2023 - nature.com
Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes. The
progressive shortening of steady-state telomere length in normal human somatic cells is a …
progressive shortening of steady-state telomere length in normal human somatic cells is a …
Cellular senescence: when bad things happen to good cells
J Campisi, F d'Adda di Fagagna - Nature reviews Molecular cell biology, 2007 - nature.com
Cells continually experience stress and damage from exogenous and endogenous sources,
and their responses range from complete recovery to cell death. Proliferating cells can …
and their responses range from complete recovery to cell death. Proliferating cells can …
Telomeres and human disease: ageing, cancer and beyond
MA Blasco - Nature Reviews Genetics, 2005 - nature.com
Telomere length and telomerase activity are important factors in the pathobiology of human
disease. Age-related diseases and premature ageing syndromes are characterized by short …
disease. Age-related diseases and premature ageing syndromes are characterized by short …
[HTML][HTML] Cellular senescence in cancer and aging
Cellular senescence, a state of irreversible growth arrest, can be triggered by multiple
mechanisms including telomere shortening, the epigenetic derepression of the INK4a/ARF …
mechanisms including telomere shortening, the epigenetic derepression of the INK4a/ARF …
Challenges in glioblastoma immunotherapy: mechanisms of resistance and therapeutic approaches to overcome them
KJ Habashy, R Mansour, C Moussalem… - British journal of …, 2022 - nature.com
Glioblastoma is the most common and aggressive primary malignant brain tumour. The
prognosis of patients with glioblastoma is poor, and their overall survival averages at 1 year …
prognosis of patients with glioblastoma is poor, and their overall survival averages at 1 year …
RNA-binding proteins in human genetic disease
RNA-binding proteins (RBPs) are key components in RNA metabolism, regulating the
temporal, spatial and functional dynamics of RNAs. Altering the expression of RBPs has …
temporal, spatial and functional dynamics of RNAs. Altering the expression of RBPs has …
Telomere length, stem cells and aging
MA Blasco - Nature chemical biology, 2007 - nature.com
Telomere shortening occurs concomitant with organismal aging, and it is accelerated in the
context of human diseases associated with mutations in telomerase, such as some cases of …
context of human diseases associated with mutations in telomerase, such as some cases of …
Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
MM Ho, AV Ng, S Lam, JY Hung - Cancer research, 2007 - AACR
Stem cells have been isolated by their ability to efflux Hoechst 33342 dye and are referred to
as the “side population”(SP). In this study, we used flow cytometry and Hoechst 33342 dye …
as the “side population”(SP). In this study, we used flow cytometry and Hoechst 33342 dye …