[PDF][PDF] Consensus recommendations for optimising the diagnosis and treatment of paroxysmal nocturnal haemoglobinuria in Singapore

YT Goh, ES Yap, CW Tan, D Tan, YSM Loh… - Ann. Acad. Med …, 2024 - annals.edu.sg
Introduction: Paroxysmal nocturnal haemoglobinuria (PNH) is a rare haematologic disease
characterised by intravascular haemolysis, thrombophilia and bone marrow failure. There is …

[HTML][HTML] Thrombosis in Paroxysmal Nocturnal Hemoglobinuria (PNH): From Pathogenesis to Treatment

S Kokoris, A Polyviou, P Evangelidis, E Grouzi… - International Journal of …, 2024 - mdpi.com
Paroxysmal Nocturnal Hemoglobinuria (PNH) constitutes a rare bone marrow failure
syndrome characterized by hemolytic anemia, thrombotic events (TEs), and bone marrow …

Health-related quality of life and influencing factors of patients with paroxysmal nocturnal hemoglobinuria in China

H Yu, S Duan, P Wang, R Fu, Z Lv, Y Yu, P Miao… - Orphanet Journal of …, 2024 - Springer
Background Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder, leading
to various complications and impairments in patients' health-related quality of life (HRQOL) …

[HTML][HTML] Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria

V Giudice, P Scala, EP Lamparelli, M Gorrese, B Serio… - Iscience, 2024 - cell.com
Nano-vesicular carriers are promising tissue-specific drug delivery platforms. Here,
biomimetic proteolipid vesicles (BPLVs) were used for delivery of …

Safety Profile of Monoclonal Antibodies and Subsequent Drug Developments in the Treatment of Paroxysmal Nocturnal Hemoglobinuria

V Mallenahalli Neeekantappa, A Kamath… - Medicina, 2024 - mdpi.com
Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disease characterized by
intravascular hemolysis due to the targeting of affected red blood cells by the complement …

Safety and efficacy of danicopan in patients with paroxysmal nocturnal hemoglobinuria: a systematic review and meta-analysis

E Muvaffak, ME Mokresh, A Varda… - Expert Review of …, 2024 - Taylor & Francis
Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease characterized by
complement-mediated intravascular hemolysis (IVH). Current treatments like Eculizumab …

[HTML][HTML] 浙江省289 例阵发性睡眠性血红蛋白尿症患者的临床特征

许改香, 金伟媚, 叶宝东, 江松福, 胡超… - Chinese Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
目的对浙江省阵发性睡眠性血红蛋白尿症(PNH) 患者的临床特征, 治疗现状及其生存情况进行多
中心回顾性分析, 以提高对该疾病的认识和规范化诊治水平. 方法纳入了2005 年9 月至2023 年5 …

The Onerous task of managing paroxysmal nocturnal hemoglobinuria in a Low resource setting: a case report. A hematologist's experience

MK Waiswa, C Sekaggya-Wiltshire, E Seremba… - African Health …, 2024 - ajol.info
Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) is a form of red cell membrane
defect characterized by increased sensitivity to complement-mediated cell lysis, resulting in …

Paroxysmal nocturnal hemoglobinuria-related thrombosis in the era of novel therapies: a 2043 patient/years analysis

C Gurnari, H Awada, S Pagliuca, D Dima, F Ullah… - Blood, 2024 - Elsevier
Thrombophilia is one of the principal features of paroxysmal nocturnal hemoglobinuria
(PNH) and constitutes the main cause of disease morbidity/mortality. Anti-complement …

[PDF][PDF] 浙江省289 例阵发性睡眠性血红蛋白尿症患者的临床特征

姚荣欣, 陆滢, 李琳洁, 张瑾, 欧阳桂芳, 洪用伟… - pdfs.semanticscholar.org
目的对浙江省阵发性睡眠性血红蛋白尿症(PNH) 患者的临床特征, 治疗现状及其生存情况进行多
中心回顾性分析, 以提高对该疾病的认识和规范化诊治水平. 方法纳入了2005 年9 月至2023 年5 …