The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation …
PD Stenson, M Mort, EV Ball, K Evans, M Hayden… - Human genetics, 2017 - Springer
Abstract The Human Gene Mutation Database (HGMD®) constitutes a comprehensive
collection of published germline mutations in nuclear genes that underlie, or are closely …
collection of published germline mutations in nuclear genes that underlie, or are closely …
Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Genome evolution and diversity of wild and cultivated potatoes
Potato (Solanum tuberosum L.) is the world's most important non-cereal food crop, and the
vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances …
vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances …
A global catalog of whole-genome diversity from 233 primate species
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …
informative context in which to study the impact of genomic diversity on fundamental …
A high-coverage Neandertal genome from Vindija Cave in Croatia
To date, the only Neandertal genome that has been sequenced to high quality is from an
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
individual found in Southern Siberia. We sequenced the genome of a female Neandertal …
The Ensembl gene annotation system
The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …
vertebrate species across a wide range of genome projects. Furthermore, it generates the …
[图书][B] The secret of our success: How culture is driving human evolution, domesticating our species, and making us smarter
J Henrich - 2016 - degruyter.com
Humans are a puzzling species. On the one hand, we struggle to survive on our own in the
wild, often failing to overcome even basic challenges, like obtaining food, building shelters …
wild, often failing to overcome even basic challenges, like obtaining food, building shelters …
Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow
Speciation, the evolution of reproductive isolation among populations, is continuous,
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …
High-resolution comparative analysis of great ape genomes
ZN Kronenberg, IT Fiddes, D Gordon, S Murali… - Science, 2018 - science.org
INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …
standing endeavor that requires the comprehensive discovery and comparison of all forms …
Structure of the human cGAS–DNA complex reveals enhanced control of immune surveillance
Summary Cyclic GMP–AMP synthase (cGAS) recognition of cytosolic DNA is critical for
immune responses to pathogen replication, cellular stress, and cancer. Existing structures of …
immune responses to pathogen replication, cellular stress, and cancer. Existing structures of …