Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Background Dengue is an arboviral disease caused by dengue virus. Symptomatic dengue
infection causes a wide range of clinical manifestations, from mild dengue fever (DF) to …

Dengue is the world's most prevalent and important arboviral disease. More than 50% of the
world's population lives at daily risk of infection and it is estimated more than 95 million …

Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe,
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …

Flaviviruses consist of significant human pathogens responsible for hundreds of millions of
infections each year. Their antigenic relationships generate immune responses that are …

Vaccines have a history that started late in the 18th century. From the late 19th century,
vaccines could be developed in the laboratory. However, in the 20th century, it became …

Dengue virus (DENV) has become a global health threat with about half of the world's
population at risk of infection. Although the disease caused by DENV is self-limiting in the …

The Flavivirus genus is made up of viruses that are either mosquito-borne, tick-borne and
other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to …

Introduction Reports of high rates of primary microcephaly and Guillain–Barré syndrome
associated with Zika virus infection in French Polynesia and Brazil have raised concerns that …