Human gut microbiota in health and disease: Unveiling the relationship

M Afzaal, F Saeed, YA Shah, M Hussain… - Frontiers in …, 2022 - frontiersin.org
The human gut possesses millions of microbes that define a complex microbial community.
The gut microbiota has been characterized as a vital organ forming its multidirectional …

Ruminococcus gnavus: friend or foe for human health

EH Crost, E Coletto, A Bell… - FEMS Microbiology …, 2023 - academic.oup.com
Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Gut microbiota in human metabolic health and disease

Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Synergy and oxygen adaptation for development of next-generation probiotics

MT Khan, C Dwibedi, D Sundh, M Pradhan, JD Kraft… - Nature, 2023 - nature.com
The human gut microbiota has gained interest as an environmental factor that may
contribute to health or disease. The development of next-generation probiotics is a …

[HTML][HTML] Gut microbiota: an important player in type 2 diabetes mellitus

Z Zhou, B Sun, D Yu, C Zhu - Frontiers in cellular and infection …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM) is one of the common metabolic diseases in the world. Due
to the rise in morbidity and mortality, it has become a global health problem. To date, T2DM …

[HTML][HTML] Role of gut microbiota in type 2 diabetes pathophysiology

M Gurung, Z Li, H You, R Rodrigues, DB Jump… - …, 2020 - thelancet.com
A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

The gut microbiota in prediabetes and diabetes: a population-based cross-sectional study

H Wu, V Tremaroli, C Schmidt, A Lundqvist, LM Olsson… - Cell metabolism, 2020 - cell.com
The link between the gut microbiota and type 2 diabetes (T2D) warrants further investigation
because of known confounding effects from antidiabetic treatment. Here, we profiled the gut …

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

C Depommier, A Everard, C Druart, H Plovier… - Nature medicine, 2019 - nature.com
Metabolic syndrome is characterized by a constellation of comorbidities that predispose
individuals to an increased risk of developing cardiovascular pathologies as well as type 2 …

The intestinal microbiota fuelling metabolic inflammation

H Tilg, N Zmora, TE Adolph, E Elinav - Nature Reviews Immunology, 2020 - nature.com
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems

Y Xu, N Wang, HY Tan, S Li, C Zhang… - Frontiers in …, 2020 - frontiersin.org
Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a
worldwide epidemic and are intimately linked to diet. The gut microbiota interaction has …