The comet assay (single cell gel electrophoresis) is the most common method for measuring
DNA damage in eukaryotic cells or disaggregated tissues. The assay depends on the …

Over a century ago, Theodor Boveri paved the way to mechanistic studies linking
chromosomal abnormalities to cancer pathogenesis. Since then, theoretical and empirical …

The question of what constitutes an acceptable risk is a matter of judgement. Such decisions
are multifaceted and complex, and involve a balance of risk and benefit. High risks may be …

The frequency of micronuclei (MN) in peripheral blood lymphocytes (PBL) is extensively
used as a biomarker of chromosomal damage and genome stability in human populations …

The purpose of these guidelines is to provide concise guidance on the planning, performing
and interpretation of studies to monitor groups or individuals exposed to genotoxic agents …

OBJECTIVE To review literature documenting associations between pesticide use and
cancer. DATA SOURCES We searched MEDLINE, PreMedline, CancerLit, and LILACS to …

DNA double-strand breaks (DSB) are considered to be critical primary lesions in the
formation of chromosomal aberrations. DSB may be induced by exogenous agents, such as …

The comet assay is widely used in human biomonitoring to measure DNA damage as a
marker of exposure to genotoxic agents or to investigate genoprotective effects. Studies …

Formaldehyde is an economically important chemical, to which more than 2 million US
workers are occupationally exposed. Substantially more people are exposed to …

The comet assay or single cell gel electrophoresis, is the most common method used to
measure strand breaks and a variety of other DNA lesions in human populations. To …