Disturbance in the neuronal network leads to instability in the microtubule (MT) railroad of
axons, causing hindrance in the intra-axonal transport and making it difficult to re-establish …

Interleukin-6 (IL-6) is a versatile cytokine crucial for immune response modulation,
inflammation regulation, and various physiological processes in the body. Its wide-ranging …

Paclitaxel is widely used to treat cancer, however, drug resistance limits its clinical utility.
STAT3 is constitutively activated in some cancers, and contributes to chemotherapy …

One important facet of glaucoma pathophysiology is axonal damage, which ultimately
disrupts the connection between the retina and its postsynaptic brain targets. The concurrent …

Cystic glioblastomas are aggressive primary brain tumors that may both destroy and
displace the surrounding brain tissue as they grow. The mechanisms underlying these …

The key regulators and regeneration-associated genes involved in axonal regeneration of
neurons after injury have not been clarified. In high-throughput sequencing, various factors …

Purpose To evaluate systemic trans-signalling of interleukin (IL)-6 in patients with primary
open-angle glaucoma (POAG). Methods Fifty-one POAG patients and 47 matched healthy …