Nearly 40 years ago, the Sagawa laboratory spawned a renaissance in the use of
instantaneous ventricular pressure-volume (PV) relations to assess cardiac function. Since …

We aimed to quantify kinetic energy (KE) during the entire cardiac cycle of the left ventricle
(LV) and right ventricle (RV) using four-dimensional phase-contrast magnetic resonance …

Kinetic energy (KE) of atrial blood has been postulated as a possible contributor to
ventricular filling. Therefore, we aimed to quantify the left (LA) and right (RA) atrial blood KE …

Background—Pseudonormal Doppler E-wave filling patterns indicate diastolic dysfunction
but are indistinguishable from the normal filling pattern. For accurate classification …

The slope of the diastatic pressure–volume relationship (D-PVR) defines passive left
ventricular (LV) stiffness K. Although K is a relative measure, cardiac catheterization, which …

Conventional echocardiographic diastolic function (DF) assessment approximates
transmitral flow velocity contours (Doppler E-waves) as triangles, with peak (E peak) …

The mechanical suction-pump feature of the left ventricle aspirates atrial blood and
generates a rapid rise and fall in transmitral flow (Doppler E-wave). Initially, E-wave …

Kinetic energy (KE) of intracardiac blood flow reflects myocardial work spent on accelerating
blood and provides a mechanistic window into diastolic filling dynamics. Diastolic …

Although the electrophysiologic derangement responsible for atrial fibrillation (AF) has been
elucidated, how AF remodels the ventricular chamber and affects diastolic function (DF) has …

Although catheterization is the gold standard, Doppler echocardiography is the preferred
diastolic function (DF) characterization method. The physiology of diastole requires …