Molecular alterations in meningioma: prognostic and therapeutic perspectives

C Birzu, M Peyre, F Sahm - Current Opinion in Oncology, 2020 - journals.lww.com
The mutational landscape of meningioma has expanded following the use of the new
genetic sequencing approaches. Novel mutations have been characterized and reveal their …

Estrogen and progesterone therapy and meningiomas

M Hage, O Plesa, I Lemaire, ML Raffin Sanson - Endocrinology, 2022 - academic.oup.com
Meningiomas are common intracranial tumors with a female predominance. Their etiology is
still poorly documented. The role of sexual hormones has long been evoked, and data have …

Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study

A Weill, P Nguyen, M Labidi, B Cadier, T Passeri… - bmj, 2021 - bmj.com
Objective To assess the risk of meningioma associated with use of high dose cyproterone
acetate, a progestogen indicated for clinical hyperandrogenism. Design Observational …

Risk of intracranial meningioma with three potent progestogens: A population‐based case–control study

L Hoisnard, M Laanani, T Passeri… - European Journal of …, 2022 - Wiley Online Library
Background and purpose A dose‐dependent association between the use of cyproterone
acetate (CPA) and intracranial meningioma has been identified but data for other potent …

Female gender and exogenous progesterone exposition as risk factors for spheno-orbital meningiomas

C Apra, P Roblot, A Alkhayri, C Le Guérinel… - Journal of Neuro …, 2020 - Springer
Objective The great heterogeneity of meningiomas is challenging and we need to
distinguish relevant subgroups. Spheno-orbital osteomeningiomas (SOOM) constitute a …

Meningioma in patients exposed to progestin drugs: results from a real-life screening program

T Samoyeau, C Provost, A Roux, L Legrand… - Journal of Neuro …, 2022 - Springer
Purpose To report the results of systematic meningioma screening program implemented by
French authorities in patients exposed to progestin therapies (cyproterone (CPA) …

Brain-invasive meningiomas: molecular mechanisms and potential therapeutic options

C Qin, M Huang, Y Pan, Y Li, W Long, Q Liu - Brain Tumor Pathology, 2021 - Springer
Meningiomas are the most commonly diagnosed benign intracranial adult tumors. Subsets
of meningiomas that present with extensive invasion into surrounding brain areas have high …

Meningiomas in patients with long-term exposition to progestins: characteristics and outcome

T Graillon, S Boissonneau, R Appay, M Boucekine… - Neurochirurgie, 2021 - Elsevier
Objective The aim of this study was to describe progestin-associated meningiomas'
characteristics, outcome and management. Material and methods We included 53 patients …

Intracranial meningiomas decrease in volume on magnetic resonance imaging after discontinuing progestin

EHJ Voormolen, PO Champagne, E Roca… - …, 2021 - journals.lww.com
OBJECTIVE To investigate the relationship between growth kinetics of intracranial
meningiomas and usage of the progestin cyproterone acetate (PCA). METHODS This study …

Development and growth of intracranial meningiomas in transgender women taking cyproterone acetate as gender-affirming progestogen therapy: a systematic review

CP Millward, SM Keshwara, AI Islim… - Transgender …, 2022 - liebertpub.com
Background: Gender-affirming hormone therapy is critical to the management of transgender
persons. Cyproterone acetate (CPA) is a synthetic, progesterone-like compound commonly …