Osteoporosis is a common disorder, affecting hundreds of millions of people worldwide, and
characterized by decreased bone mineral density and increased fracture risk. Known …

Mesenchymal stem cells (MSCs) have been identified in many adult tissues and they have
been closely studied in recent years, especially in view of their potential use for treating …

MicroRNAs are fine regulators of the whole-body adaptive response but their use as
biomarkers is limited by the lack of standardized pre-and post-analytical procedures. This …

Osteoclasts are the exclusive cells of bone resorption. Abnormally activating osteoclasts can
lead to low bone mineral density, which will cause osteopenia, osteoporosis, and other bone …

As implantable materials, titanium, and its alloys have garnered enormous interest from
researchers for dental and orthopedic procedures. Despite their success in wide clinical …

This paper addresses a significant paradox in biomaterials science; biocompatibility
phenomena have been experienced and described for over 50 years but without an agreed …

MicroRNAs (miRNAs) are endogenous small noncoding~ 22-nt RNAs, which have been
reported to play a crucial role in maintaining bone development and metabolism …

Implant loosening is still the major form of the failure of artificial joints. Herein, inspired by the
operculum of the river snail, we prepared a novel bionic micro/nanoscale topography on a …

Understanding the molecular events that regulate osteoblast differentiation is essential for
the development of effective approaches to bone regeneration. In this study, we analysed …

The role of skeletal muscle in the pathophysiology of knee OA is poorly understood. To date,
the majority of literature has focused on the association of muscle strength with OA …