Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Glycosylation is the most abundant and diverse form of post-translational modification of
proteins that is common to all eukaryotic cells. Enzymatic glycosylation of proteins involves a …

Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

A unique glycan-binding protein expressed in macrophages and some types of other
immune cells is the mannose receptor (MR, CD206). It is an endocytic, transmembrane …

N-Glycoproteomics, the system-wide study of glycans asparagine-linked to protein carriers,
holds a unique and still largely untapped potential to provide deep insights into the …

Highlights•Recent advancements in glycoinformatics tools to support analysis of glycan and
glycopeptide data sets are summarised.•Review summarises the growth of machine …

The 2021 Metrics of the HUPO Human Proteome Project (HPP) show that protein expression
has now been credibly detected (neXtProt PE1 level) for 18 357 (92.8%) of the 19 778 …

Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …

N-glycosylation is an abundant post-translational modification of most cell-surface proteins.
N-glycans play a crucial role in cellular functions like protein folding, protein localization, cell …