Maximizing safe resection of low-and high-grade glioma

SL Hervey-Jumper, MS Berger - Journal of neuro-oncology, 2016 - Springer
Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

Radiomics in brain tumor: image assessment, quantitative feature descriptors, and machine-learning approaches

M Zhou, J Scott, B Chaudhury, L Hall… - American Journal …, 2018 - Am Soc Neuroradiology
Radiomics describes a broad set of computational methods that extract quantitative features
from radiographic images. The resulting features can be used to inform imaging diagnosis …

Predicting cancer outcomes from histology and genomics using convolutional networks

P Mobadersany, S Yousefi, M Amgad… - Proceedings of the …, 2018 - National Acad Sciences
Cancer histology reflects underlying molecular processes and disease progression and
contains rich phenotypic information that is predictive of patient outcomes. In this study, we …

T2–FLAIR mismatch, an imaging biomarker for IDH and 1p/19q status in lower-grade gliomas: a TCGA/TCIA project

SH Patel, LM Poisson, DJ Brat, Y Zhou, L Cooper… - Clinical cancer …, 2017 - AACR
Purpose: Lower-grade gliomas (WHO grade II/III) have been classified into clinically relevant
molecular subtypes based on IDH and 1p/19q mutation status. The purpose was to …

MRI features predict survival and molecular markers in diffuse lower-grade gliomas

H Zhou, M Vallières, HX Bai, C Su, H Tang… - Neuro …, 2017 - academic.oup.com
Background. Previous studies have shown that MR imaging features can be used to predict
survival and molecular profile of glioblastoma. However, no study of a similar type has been …

3D deep learning for multi-modal imaging-guided survival time prediction of brain tumor patients

D Nie, H Zhang, E Adeli, L Liu, D Shen - … 17-21, 2016, Proceedings, Part II …, 2016 - Springer
High-grade glioma is the most aggressive and severe brain tumor that leads to death of
almost 50% patients in 1–2 years. Thus, accurate prognosis for glioma patients would …

Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period

SL Hervey-Jumper, J Li, D Lau, AM Molinaro… - Journal of …, 2015 - thejns.org
OBJECT Awake craniotomy is currently a useful surgical approach to help identify and
preserve functional areas during cortical and subcortical tumor resections. Methodologies …

Radiomic features from the peritumoral brain parenchyma on treatment-naive multi-parametric MR imaging predict long versus short-term survival in glioblastoma …

P Prasanna, J Patel, S Partovi, A Madabhushi… - European …, 2017 - Springer
Objective Despite 90% of glioblastoma (GBM) recurrences occurring in the peritumoral brain
zone (PBZ), its contribution in patient survival is poorly understood. The current study …

MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set

DA Gutman, LAD Cooper, SN Hwang, CA Holder… - Radiology, 2013 - pubs.rsna.org
Purpose To conduct a comprehensive analysis of radiologist-made assessments of
glioblastoma (GBM) tumor size and composition by using a community-developed controlled …

Glioma extent of resection and its impact on patient outcome

N Sanai, MS Berger - Neurosurgery, 2008 - journals.lww.com
OBJECTIVE: There is still no general consensus in the literature regarding the role of extent
of glioma resection in improving patient outcome. Although the importance of resection in …