Peptide-enabled targeted delivery systems for therapeutic applications

M Liu, X Fang, Y Yang, C Wang - Frontiers in bioengineering and …, 2021 - frontiersin.org
Receptor-targeting peptides have been extensively pursued for improving binding specificity
and effective accumulation of drugs at the site of interest, and have remained challenging for …

Bioinspired intrinsic versatile hydrogel fabricated by amyloidal toxin simulant‐based nanofibrous assemblies for accelerated diabetic wound healing

Q Xuan, F Jiang, H Dong, W Zhang… - Advanced Functional …, 2021 - Wiley Online Library
Persistent microbial infection and decreased neovascularization are common issues
associated with diabetic wound treatment. Hydrogel dressings that offer intrinsic …

Advances in hybrid peptide-based self-assembly systems and their applications

A Boruah, A Roy - Biomaterials Science, 2022 - pubs.rsc.org
Self-assembly of peptides demonstrates a great potential for designing highly ordered, finely
tailored supramolecular arrangements enriched with high specificity, improved efficacy and …

Peptide binder with high-affinity for the SARS-CoV-2 spike receptor-binding domain

L Yu, R Wang, T Wen, L Liu, T Wang, S Liu… - … Applied Materials & …, 2022 - ACS Publications
Rapid antigen detection tests are urgently needed for the early diagnosis of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The discovery of a binder with high …

Facile Reactive Oxygen Species-Scavenging Supramolecular Hydrogel to Promote Diabetic Wound Healing

D Jia, S Li, M Jiang, Z Lv, H Wang… - ACS Applied Materials & …, 2024 - ACS Publications
Chronic wound healing impairment is a significant complication in diabetes. Hydrogels that
maintain wound moisture and enable sustained drug release have become prominent for …

Rational biological interface engineering: Amyloidal supramolecular microstructure-inspired hydrogel

Q Xuan, Y Wang, C Chen, P Wang - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Amyloidal proteins, which are prone to form fibrillar and ordered aggregates in vivo and in
vitro, underlie the mechanism for neurodegenerative disorders and also play essential …

Interactions of SARS-CoV-2 and MERS-CoV fusion peptides measured using single-molecule force methods

C Qiu, GR Whittaker, SH Gellman, S Daniel… - Biophysical Journal, 2023 - cell.com
We address the challenge of understanding how hydrophobic interactions are encoded by
fusion peptide (FP) sequences within coronavirus (CoV) spike proteins. Within the FPs of …

Ultrasound-Induced Amino Acid-Based Hydrogels With Superior Mechanical Strength for Controllable Long-Term Release of Anti-Cercariae Drug

L Ling, L Zhu, Y Li, C Liu, L Cheng - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Stimulus-responsive hydrogels are significantly programmable materials that show potential
applications in the field of biomedicine and the environment. Ultrasound as a stimulus can …

Conservation and identity selection of cationic residues flanking the hydrophobic regions in intermediate filament superfamily

W Zhang, M Liu, RL Dupont, K Huang, L Yu… - Frontiers in …, 2021 - frontiersin.org
The interplay between the hydrophobic interactions generated by the nonpolar region and
the proximal functional groups within nanometers of the nonpolar region offers a promising …

Perturbation effect of single polar group substitution on the self-association of amphiphilic peptide helices

W Zhang, M Liu, L Yu, S Mo, Z Deng, S Liu… - Journal of Colloid and …, 2022 - Elsevier
As an important attempt towards creating hierarchical structures more like nature, the
peptide is employed as a building block to build supramolecular architectures. An emerging …