Physiological closed-loop control (PCLC) systems: Review of a modern frontier in automation
Over the past decade, there has been an unprecedented international focus on improved
quality and availability of medical care, which has reignited interest in clinical automation …
quality and availability of medical care, which has reignited interest in clinical automation …
Use of 3D anatomical models in mock circulatory loops for cardiac medical device testing
Abstract Introduction Mock circulatory loops (MCLs) are mechanical representations of the
cardiovascular system largely used to test the hemodynamic performance of cardiovascular …
cardiovascular system largely used to test the hemodynamic performance of cardiovascular …
Estimating model uncertainty of neural networks in sparse information form
We present a sparse representation of model uncertainty for Deep Neural Networks (DNNs)
where the parameter posterior is approximated with an inverse formulation of the …
where the parameter posterior is approximated with an inverse formulation of the …
Continuous heart volume monitoring by fully implantable soft strain sensor
SA Dual, B Llerena Zambrano… - Advanced …, 2020 - Wiley Online Library
Cardiothoracic open‐heart surgery has revolutionized the treatment of cardiovascular
disease, the leading cause of death worldwide. After the surgery, hemodynamic and volume …
disease, the leading cause of death worldwide. After the surgery, hemodynamic and volume …
An in vitro model to study suction events by a ventricular assist device: validation with clinical data
Introduction: Ventricular assist devices (LVADs) are a valuable therapy for end-stage heart
failure patients. However, some adverse events still persist, such as suction that can trigger …
failure patients. However, some adverse events still persist, such as suction that can trigger …
Circulatory Support: Artificial Muscles for the Future of Cardiovascular Assist Devices
I Pirozzi, A Kight, AK Han, MR Cutkosky… - Advanced …, 2023 - Wiley Online Library
Artificial muscles enable the design of soft implantable devices which are poised to
transform the way we mechanically support the heart today. Heart failure is a prevalent and …
transform the way we mechanically support the heart today. Heart failure is a prevalent and …
Physiologic data-driven iterative learning control for left ventricular assist devices
Continuous flow ventricular assist devices (cfVADs) constitute a viable and increasingly
used therapy for end-stage heart failure patients. However, they are still operating at a fixed …
used therapy for end-stage heart failure patients. However, they are still operating at a fixed …
Non-linearity of end-systolic pressure–volume relation in afterload increases is caused by an overlay of shortening deactivation and the Frank–Starling mechanism
MA Habigt, M Krieger, J Gesenhues, M Ketelhut… - Scientific Reports, 2021 - nature.com
The linearity and load insensitivity of the end-systolic pressure–volume-relationship
(ESPVR), a parameter that describes the ventricular contractile state, are controversial. We …
(ESPVR), a parameter that describes the ventricular contractile state, are controversial. We …
A sensorless modular multiobjective control algorithm for left ventricular assist devices: A clinical pilot study
M Maw, T Schlöglhofer, C Marko, P Aigner… - Frontiers in …, 2022 - frontiersin.org
Background Contemporary Left Ventricular Assist Devices (LVADs) mainly operate at a
constant speed, only insufficiently adapting to changes in patient demand. Automatic …
constant speed, only insufficiently adapting to changes in patient demand. Automatic …
Ultrasonic sensor concept to fit a ventricular assist device cannula evaluated using geometrically accurate heart phantoms
SA Dual, JM Zimmermann, J Neuenschwander… - Artificial …, 2019 - Wiley Online Library
Future left ventricular assist devices (LVADs) are expected to respond to the physiologic
need of patients; however, they still lack reliable pressure or volume sensors for feedback …
need of patients; however, they still lack reliable pressure or volume sensors for feedback …