Liddle syndrome is an inherited form of low-renin hypertension, transmitted with an
autosomal dominant pattern. The molecular basis of Liddle syndrome resides in germline …

Introduction Hypertensive disorders of pregnancy affect approximately one in 10
pregnancies and are associated with increased risk of adverse fetal, neonatal and maternal …

Objectives: Select appropriate pharmacological agents, including epithelial sodium channel
blockers, as first-line therapy for managing hypertension and electrolyte abnormalities in …

BACKGROUND Liddle syndrome (LS), an autosomal dominant disorder, is a common
monogenic hypertension in pediatrics. In this study, we reported a novel SCNN1G variant in …

Liddle syndrome is an autosomal dominant form of monogenic hypertension that is caused
by mutations in SCNN1A, SCNN1B or SCNN1G, which respectively encode the α, β and γ …

Aldosterone is a mineralocorticoid hormone that increases sodium (ie, salt) and water (ie,
fluid) retention, ultimately increasing blood pressure.[1] Aldosterone also increases …

Objective To investigate the prevalence and aetiology of hypokalaemia in pregnancy.
Methods This was a five-year retrospective audit of women who received care at a tertiary …

Introduction: Liddle syndrome is an autosomal dominant monogenic disease that mainly
manifests as early-onset hypertension, hypokalaemia and metabolic alkalosis, as well as …

Mineralocorticoid receptor antagonists are highly effective in the management of resistant
hypertension and primary hyperaldosteronism. Recent studies demonstrate that …

Pregnancy is a state wherein there are several physiological hormonal changes. Moreover,
hypertension is common during pregnancy. A number of hormonal alterations could induce …