The roles of microglia and astrocytes in phagocytosis and myelination: Insights from the cuprizone model of multiple sclerosis

MK Sen, DA Mahns, JR Coorssen, PJ Shortland - Glia, 2022 - Wiley Online Library
In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between
demyelination and remyelination can trigger progressive degenerative processes. The …

Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials

B Conklin, BM Conley, Y Hou, M Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Various types of inorganic nanomaterials are capable of diagnostic biomarker detection and
the therapeutic delivery of a disease or inflammatory modulating agent. Those multi …

Proteomics of multiple sclerosis: inherent issues in defining the pathoetiology and identifying (early) biomarkers

MK Sen, MSM Almuslehi, PJ Shortland… - International Journal of …, 2021 - mdpi.com
Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …

The Relationship Between Myelin Basic Protein mRna and Glial Cell Populations in the Murine Cervical Spinal Cord

EM Wilion - 2023 - search.proquest.com
A functional nervous system is necessary for the survival of all but the simplest of animal
species and myelin is one imperative feature which allows the vertebrate nervous system to …

[PDF][PDF] Luman/CREB3 is a Novel Regulator of Survival and Myelinating Capacity of Myelinating Glial Cells

JM Naniong - 2022 - harvest.usask.ca
An emerging feature of demyelinating disorders or events following peripheral nerve injury
is the accumulation of misfolded proteins in myelinating glia leading to activation of the …