Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
worldwide and is often associated with aspects of metabolic syndrome. Despite its …
[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …
continually shapes host pathophysiological responses. Despite readily available abundant …
Interactions between gut microbiota and polyphenols: A mechanistic and metabolomic review
H Cheng, D Zhang, J Wu, J Liu, Y Zhou, Y Tan, W Feng… - Phytomedicine, 2023 - Elsevier
Background Polyphenols are a class of naturally sourced compounds with widespread
distribution and an extensive array of bioactivities. However, due to their complex …
distribution and an extensive array of bioactivities. However, due to their complex …
[HTML][HTML] Intestinal absorption of bile acids in health and disease
AL Ticho, P Malhotra, PK Dudeja, RK Gill… - Comprehensive …, 2019 - ncbi.nlm.nih.gov
The intestinal reclamation of bile acids is crucial for the maintenance of their enterohepatic
circulation. The majority of bile acids are actively absorbed via specific transport proteins …
circulation. The majority of bile acids are actively absorbed via specific transport proteins …
[HTML][HTML] Gut microbiome and bile acids in obesity-related diseases
Dysbiosis has been implemented in the etiologies of obesity-related chronic diseases such
as type 2 diabetes, NAFLD and cardiovascular diseases. Bile acids, a class of amphipathic …
as type 2 diabetes, NAFLD and cardiovascular diseases. Bile acids, a class of amphipathic …
Postbiotics: Metabolites and mechanisms involved in microbiota-host interactions
MCG Peluzio, JA Martinez, FI Milagro - Trends in Food Science & …, 2021 - Elsevier
Background The knowledge on the mechanisms through which the metabolites produced by
the gut microbiota (postbiotics) prevent diseases, induce therapeutic responses, and behave …
the gut microbiota (postbiotics) prevent diseases, induce therapeutic responses, and behave …
Microbial metabolites as modulators of the infant gut microbiome and host-microbial interactions in early life
The development of infant gut microbiome is a pivotal process affecting the ecology and
function of the microbiome, as well as host health. While the establishment of the infant …
function of the microbiome, as well as host health. While the establishment of the infant …
[HTML][HTML] Berberine improves DSS-induced colitis in mice by modulating the fecal-bacteria-related bile acid metabolism
X Sun, Y Zhang, G Cheng, T Zhu, Z Zhang… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) has been confirmed as a disease with a high incidence and low cure
rate worldwide. In severe cases, UC can develop into colon cancer. Modern research has …
rate worldwide. In severe cases, UC can develop into colon cancer. Modern research has …
Rational design of polymeric micelles for targeted therapeutic delivery
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
An update of pharmacological management in children with functional constipation
A de Geus, IJN Koppen, RB Flint, MA Benninga… - Pediatric Drugs, 2023 - Springer
Functional constipation is a common problem in childhood worldwide and has a great
impact on social, physical, and emotional functioning of affected children and their …
impact on social, physical, and emotional functioning of affected children and their …