Extracellular calcium sensing and extracellular calcium signaling
EM Brown, RJ MacLeod - Physiological reviews, 2001 - journals.physiology.org
The cloning of a G protein-coupled extracellular Ca2+ (Cao 2+)-sensing receptor (CaR) has
elucidated the molecular basis for many of the previously recognized effects of Cao 2+ on …
elucidated the molecular basis for many of the previously recognized effects of Cao 2+ on …
Molecular and cellular mechanisms of excitotoxic neuronal death
Y Wang, Z Qin - Apoptosis, 2010 - Springer
Glutamate receptor-mediated excitatory neurotransmission plays a key role in neural
development, differentiation and synaptic plasticity. However, excessive stimulation of …
development, differentiation and synaptic plasticity. However, excessive stimulation of …
Hypoxia-ischemia and retinal ganglion cell damage
C Kaur, WS Foulds, EA Ling - Clinical ophthalmology, 2008 - Taylor & Francis
Retinal hypoxia is the potentially blinding mechanism underlying a number of sight-
threatening disorders including central retinal artery occlusion, ischemic central retinal vein …
threatening disorders including central retinal artery occlusion, ischemic central retinal vein …
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs
Metabotropic glutamate (mGlu) receptors have been considered as potential targets for
neuroprotective drugs, but the lack of specific drugs has limited the development of …
neuroprotective drugs, but the lack of specific drugs has limited the development of …
Amyloid beta-related alterations to glutamate signaling dynamics during Alzheimer's disease progression
Alzheimer's disease (AD) ranks sixth on the Centers for Disease Control and Prevention Top
10 Leading Causes of Death list for 2016, and the Alzheimer's Association attributes 60% to …
10 Leading Causes of Death list for 2016, and the Alzheimer's Association attributes 60% to …
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons
Medium spiny neurons were recorded from striatal slices obtained from mice lacking the
group I metabotropic glutamate receptor (mGluR) subtype 1 or subtype 5. In wild-type …
group I metabotropic glutamate receptor (mGluR) subtype 1 or subtype 5. In wild-type …
Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders?
Metabotropic glutamate (mGlu) receptors are a large, heterogeneous family of G-protein
coupled receptors, which modulate excitatory synaptic transmission through various …
coupled receptors, which modulate excitatory synaptic transmission through various …
Synaptic transmission in the striatum: from plasticity to neurodegeneration
P Calabresi, D Centonze, P Gubellini, GA Marfia… - Progress in …, 2000 - Elsevier
Striatal neurones receive myriad of synaptic inputs originating from different sources.
Massive afferents from all areas of the cortex and the thalamus represent the most important …
Massive afferents from all areas of the cortex and the thalamus represent the most important …
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-β
V Bruno, G Battaglia, G Casabona… - Journal of …, 1998 - Soc Neuroscience
The medium collected from cultured astrocytes transiently exposed to the group-II
metabotropic glutamate (mGlu) receptor agonists (2S, 1′ R, 2′ R, 3′ R)-2-(2, 3 …
metabotropic glutamate (mGlu) receptor agonists (2S, 1′ R, 2′ R, 3′ R)-2-(2, 3 …
Group I metabotropic glutamate receptors: implications for brain diseases
F Bordi, A Ugolini - Progress in neurobiology, 1999 - Elsevier
Glutamate is the major excitatory neurotransmitter in the brain and plays a unique role in a
variety of central nervous system (CNS) functions. The discovery of the metabotropic …
variety of central nervous system (CNS) functions. The discovery of the metabotropic …