CXCR3 in T cell function

JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 ligands: redundant, collaborative and antagonistic functions

JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

CXCR3 ligands in disease and therapy

K Van Raemdonck, PE Van den Steen… - Cytokine & growth factor …, 2015 - Elsevier
Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

International union of pharmacology. XXII. Nomenclature for chemokine receptors

PM Murphy, M Baggiolini, IF Charo, CA Hébert… - Pharmacological …, 2000 - ASPET
Chemokine receptors comprise a large family of seven transmembrane domain G protein-
coupled receptors differentially expressed in diverse cell types. Biological activities have …

IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking

JH Dufour, M Dziejman, MT Liu, JH Leung… - The Journal of …, 2002 - journals.aai.org
Abstract IFN-γ-inducible protein 10 (IP-10, CXCL10), a chemokine secreted from cells
stimulated with type I and II IFNs and LPS, is a chemoattractant for activated T cells …

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

JA Burger, TJ Kipps - Blood, 2006 - ashpublications.org
Signals from the microenvironment have a profound influence on the maintenance and/or
progression of hematopoietic and epithelial cancers. Mesenchymal or marrow-derived …

Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1

JA Burger, N Tsukada, M Burger… - Blood, The Journal …, 2000 - ashpublications.org
A subset of blood cells from patients with B-cell chronic lymphocytic leukemia (CLL)
spontaneously differentiates in vitro into large, round, or fibroblast-like adherent cells that …

Chronic lymphocytic leukemia: revelations from the B-cell receptor

FK Stevenson, F Caligaris-Cappio - Blood, 2004 - ashpublications.org
The finding that chronic lymphocytic leukemia (CLL) consists of 2 clinical subsets,
distinguished by the incidence of somatic mutations in the immunoglobulin (Ig) variable …

Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12

AK Singh, RK Arya, AK Trivedi, S Sanyal… - Cytokine & growth factor …, 2013 - Elsevier
Although chemokines are well established to function in immunity and endothelial cell
activation and proliferation, a rapidly growing literature suggests that CXC Chemokine …

Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1–transformed T cells

O Yoshie, R Fujisawa, T Nakayama… - Blood, The Journal …, 2002 - ashpublications.org
Chemokines and chemokine receptors play important roles in migration and tissue
localization of various lymphocyte subsets. Here, we report the highly frequent expression of …