[HTML][HTML] Analytical challenges and solutions for performing metabolomic analysis of root exudates

ME Casas, V Matamoros - Trends in Environmental Analytical Chemistry, 2021 - Elsevier
Plant stress responses are mediated by the release of chemical compounds called exudates
into the rhizosphere. These chemical substances include primary and secondary plant …

The role of metabolomics in informing strategies for improving photosynthesis

P Westhoff, APM Weber - Journal of Experimental Botany, 2024 - academic.oup.com
Photosynthesis plays a vital role in acclimating to and mitigating climate change, providing
food and energy security for a population that is constantly growing, and achieving an …

[HTML][HTML] Autoantibodies targeting malondialdehyde-modifications in rheumatoid arthritis regulate osteoclasts via inducing glycolysis and lipid biosynthesis

K Sakuraba, A Krishnamurthy, J Sun, X Zheng… - Journal of …, 2022 - Elsevier
Proteins subjected to post-translational modifications, such as citrullination, carbamylation,
acetylation or malondialdehyde (MDA)-modification are targeted by autoantibodies in …

[HTML][HTML] Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii

N Xia, X Guo, Q Guo, N Gupta, N Ji, B Shen… - PLoS …, 2022 - journals.plos.org
Metabolic pathways underpin the growth and virulence of intracellular parasites and are
therefore promising antiparasitic targets. The pentose phosphate pathway (PPP) is vital in …

Ultrasensitive determination of sugar phosphates in trace samples by stable isotope chemical labeling combined with RPLC–MS

S Li, FL Liu, Z Zhang, XM Yin, TT Ye, BF Yuan… - Analytical …, 2022 - ACS Publications
Sugar phosphates are important metabolic intermediates in organisms and play a vital role
in energy and central carbon metabolism. Profiling of sugar phosphates is of great …

[HTML][HTML] The phytase RipBL1 enables the assignment of a specific inositol phosphate isomer as a structural component of human kidney stones

G Liu, E Riemer, R Schneider, D Cabuzu… - RSC Chemical …, 2023 - pubs.rsc.org
Inositol phosphates (InsPs) are ubiquitous in all eukaryotes. However, since there are 63
possible different phosphate ester isomers, the analysis of InsPs is challenging. In particular …

An efficient LC-MS method for isomer separation and detection of sugars, phosphorylated sugars, and organic acids

S Koley, KL Chu, SS Gill, DK Allen - Journal of Experimental …, 2022 - academic.oup.com
Assessing central carbon metabolism in plants can be challenging due to the dynamic range
in pool sizes, with low levels of important phosphorylated sugars relative to more abundant …

[HTML][HTML] Pathogen-triggered metabolic adjustments to potato virus Y infection in potato

R Manasseh, A Berim, M Kappagantu, L Moyo… - Frontiers in Plant …, 2023 - frontiersin.org
Potato (Solanum tuberosum L) is affected by several viral pathogens with the most
economically damaging being potato virus Y (PVY). At least nine biologically distinct …

State-of-the-art in LC–MS Approaches for Probing the Polar Metabolome

A Lioupi, M Marinaki, C Virgiliou, H Gika, I Wilson… - 2021 - books.rsc.org
Metabolomics is a rapidly growing research area that focuses on the systematic study of
small molecule metabolites found in various types of biological samples, such as tissues …

[HTML][HTML] Resolution and quantification of carbohydrates by enantioselective comprehensive two-dimensional gas chromatography

AD Garcia, V Leyva, J Bocková, RL Pepino, C Meinert - Talanta, 2024 - Elsevier
Carbohydrates, in particular the d-enantiomers of ribose, 2-deoxyribose, and glucose, are
essential to life's informational biopolymers (RNA/DNA) and for supplying energy to living …