Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

WS Lee, AK Wheatley, SJ Kent, BJ DeKosky - Nature microbiology, 2020 - nature.com
Antibody-based drugs and vaccines against severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) are being expedited through preclinical and clinical development. Data …

COVID-19 Vaccine: A comprehensive status report

SP Kaur, V Gupta - Virus research, 2020 - Elsevier
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published …

[HTML][HTML] Immune response in COVID-19: A review

MA Chowdhury, N Hossain, MA Kashem… - Journal of infection and …, 2020 - Elsevier
The immune system protects us from viruses and diseases. It produces an antibody to kill
pathogen. This review shows a brief picture about the immune system to protect us from …

Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a living systematic review

I Monsef, C Doree, EM Wood… - Cochrane Database …, 2020 - cochranelibrary.com
Background Convalescent plasma and hyperimmune immunoglobulin may reduce mortality
in patients with viral respiratory diseases, and are currently being investigated in trials as …

[HTML][HTML] Convalescent plasma in Covid-19: Possible mechanisms of action

M Rojas, Y Rodríguez, DM Monsalve… - Autoimmunity …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the
coronavirus disease 2019 (COVID-19) pandemic. Therapeutic options including …

Convalescent plasma transfusion for the treatment of COVID‐19: systematic review

K Rajendran, N Krishnasamy… - Journal of medical …, 2020 - Wiley Online Library
The recent emergence of coronavirus disease 2019 (COVID‐19) pandemic has reassessed
the usefulness of historic convalescent plasma transfusion (CPT). This review was …

[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy

PK Datta, F Liu, T Fischer, J Rappaport, X Qin - Theranostics, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …

Clinical efficacy of convalescent plasma for treatment of COVID-19 infections: Results of a multicenter clinical study

H Abolghasemi, P Eshghi, AM Cheraghali… - … and Apheresis Science, 2020 - Elsevier
Since Dec. 2019 the new coronavirus (SARS-CoV-2) has infected millions and claimed life
of several hundred thousand worldwide. However, so far no approved vaccine or drug …

COVID-19 pandemic: epidemiology, etiology, conventional and non-conventional therapies

A Rauf, T Abu-Izneid, A Olatunde… - International journal of …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19), which reported in an outbreak in 2019 in Wuhan,
Hubei province, China, is caused by the SARS-CoV-2 virus. The virus belongs to the beta …

Immunology of COVID‐19: mechanisms, clinical outcome, diagnostics, and perspectives—a report of the European Academy of Allergy and Clinical Immunology …

M Sokolowska, ZM Lukasik, I Agache, CA Akdis… - Allergy, 2020 - Wiley Online Library
With the worldwide spread of the novel severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) resulting in declaration of a pandemic by the World Health Organization …