Metal-binding promiscuity in artificial metalloenzyme design

A Pordea - Current Opinion in Chemical Biology, 2015 - Elsevier
Highlights•Metalloenzyme binding sites can accommodate a diverse range of metals.•Metal
substitution can lead to novel catalytic activity.•Computational screening and rational design …

Interaction between proteins and Ir based CO releasing molecules: Mechanism of adduct formation and CO release

AA Petruk, A Vergara, D Marasco, D Bikiel… - Inorganic …, 2014 - ACS Publications
Carbon monoxide releasing molecules (CORMs) have important bactericidal, anti-
inflammatory, neuroprotective, and antiapoptotic effects and can be used as tools for CO …

Mapping the protein-binding sites for iridium (iii)-based CO-releasing molecules

M Caterino, AA Petruk, A Vergara, G Ferraro… - Dalton …, 2016 - pubs.rsc.org
A combination of mass spectrometry, Raman microspectroscopy, circular dichroism and X-
ray crystallography has been used to obtain detailed information on the reaction of an …

Investigating the adduct formation of organic mercury species with carbonic anhydrase and hemoglobin from human red blood cell hemolysate by means of LC/ESI …

J Hogeback, M Schwarzer, CA Wehe, M Sperling… - Metallomics, 2016 - academic.oup.com
The interaction of mercury species with human erythrocytes is studied to investigate possible
high molecular binding partners for mercury species. Human blood hemolysate was spiked …

Further insights into ruthenium (II) piano-stool complexes with N-alkyl imidazoles

M Djukić, MS Jeremić, R Jelić, O Klisurić, V Kojić… - Inorganica Chimica …, 2018 - Elsevier
Two piano-stool ruthenium (II) complexes [Ru (η 6-p-cymene)(N-MeIm) 3] Cl 2· 2H 2 O (1)
and [Ru (η 6-p-cymene)(N-PrIm) Cl 2](2) respectively have been synthesized and …

Coordination design of cadmium ions at the 4-fold axis channel of the apo-ferritin cage

S Abe, N Ito, B Maity, C Lu, D Lu, T Ueno - Dalton Transactions, 2019 - pubs.rsc.org
Spherical protein cages with highly symmetrical structures provide unique environments for
the conjugation of metal ions and metal nanoparticles. Ferritin has been widely studied as a …

Using hydrazine to link ferrocene with Re (CO) 3: A modular approach

K Chanawanno, HM Rhoda, A Hasheminasab… - Journal of …, 2016 - Elsevier
Acetyl ferrocene and diacetyl ferrocene both readily react with an excess of hydrazine to
afford the corresponding hydrazone compounds. These compounds can then be linked to …

Complex formation between [(η6-p-cym) Ru (H2O) 3] 2+ and oligopeptides containing three histidyl moieties

Z Bihari, V Ugone, E Garribba, N Lihi… - Journal of Organometallic …, 2016 - Elsevier
In order to model the metal ion binding capabilities of high molecular mass components of
blood the interaction between [(η 6-p-cym) Ru (H 2 O) 3] 2+ and terminally protected …

Convergent synthesis of carbonic anhydrase inhibiting bi‐heterocyclic benzamides: Structure–activity relationship and mechanistic explorations through enzyme …

FM Khan, MA Abbasi, SZ Siddiqui… - Journal of …, 2021 - Wiley Online Library
By using a convergent methodology, a novel series of N‐arylated 4‐yl‐benzamides
containing a bi‐heterocyclic thiazole–triazole core was synthesized, and the structures of …

Facile rhenium–peptide conjugate synthesis using a one-pot derived Re (CO) 3 reagent

K Chanawanno, V Kondeti, J Caporoso… - Dalton …, 2016 - pubs.rsc.org
We have synthesized two Re (CO) 3-modified lysine complexes (1 and 2), where the metal
is attached to the amino acid at the Nε position, via a one-pot Schiff base formation reaction …