Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Neurobiology of substance use in adolescents and potential therapeutic effects of exercise for prevention and treatment of substance use disorders

NL Nock, S Minnes, JL Alberts - Birth defects research, 2017 - Wiley Online Library
Substance use (eg, alcohol, marijuana, opioids, cocaine., etc,) use often initiates during
adolescence, a critical period of physiological and social development marked by an …

[HTML][HTML] Adolescent environmental enrichment induces social resilience and alters neural gene expression in a selectively bred rodent model with anxious phenotype

AM O'Connor, MH Hagenauer, LCT Forrester… - Neurobiology of …, 2024 - Elsevier
Stress is a major influence on mental health status; the ways that individuals respond to or
copes with stressors determine whether they are negatively affected in the future. Stress …

Brain and cognition for addiction medicine: From prevention to recovery neural substrates for treatment of psychostimulant-induced cognitive deficits

MS D'Souza - Frontiers in psychiatry, 2019 - frontiersin.org
Addiction to psychostimulants like cocaine, methamphetamine, and nicotine poses a
continuing medical and social challenge both in the United States and all over the world …

Neurobehavioral changes arising from early life dopamine signaling perturbations

LB Areal, RD Blakely - Neurochemistry international, 2020 - Elsevier
Dopamine (DA) signaling is critical to the modulation of multiple brain functions including
locomotion, reinforcement, attention and cognition. The literature provides strong evidence …

[PDF][PDF] The neurobiological mechanisms underlying sign-tracking behavior

BN Kuhn, P Campus, SB Flagel, A Tomie… - Sign-tracking and drug …, 2018 - researchgate.net
Pavlovian learning processes can render cues and contexts associated with drug-taking
experiences into powerful motivators, such that exposure to such stimuli can elicit drug …

Schizophrenia and neurogenesis: a stem cell approach

A Iannitelli, A Quartini, P Tirassa, G Bersani - … & Biobehavioral Reviews, 2017 - Elsevier
Several recent research findings indicate that schizophrenia (SCZ) may begin with an
abnormal neuro-genesis from embryonic Neural Stem Cells (NSCs) and that this process …

The impact of cocaine on adult hippocampal neurogenesis: potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction …

E Castilla-Ortega, DL de Guevara-Miranda… - Biochemical …, 2017 - Elsevier
After discovering that addictive drugs alter adult neurogenesis, the potential role of adult-
born hippocampal neurons in drug addiction has become a promising research field, in …

Adolescent cocaine differentially impacts psychomotor sensitization and epigenetic profiles in adult male rats with divergent affective phenotypes

A Parsegian, MJ García-Fuster, E Hebda-Bauer… - Frontiers in …, 2022 - frontiersin.org
Adolescent drug use reliably predicts increased addiction liability in adulthood, but not all
individuals are equally impacted. To explore the biological bases of this differential reactivity …

[图书][B] Sign-tracking and drug addiction

A Tomie, J Morrow - 2018 - quod.lib.umich.edu
Pavlovian learning processes can render cues and contexts associated with drug-taking
experiences into powerful motivators, such that exposure to such stimuli can elicit drug …