The mock circulatory loop (MCL) is an in vitro experimental system that can provide
continuous pulsatile flows and simulate different physiological or pathological parameters of …

Abstract Purpose of Review The purpose of this review is to synthesize and summarize
recent developments in the care of patients with end-stage heart failure being managed with …

Ventricular assist devices (VADs) offer mechanical support for patients with cardiogenic
shock by unloading the impaired ventricle and increasing cardiac outflow and subsequent …

Background: The LATERAL trial validated the safety and efficacy of the thoracotomy
approach for implantation of the HeartWare HVAD System, leading to Food and Drug …

OBJECTIVES Right ventricular failure after left ventricular assist device (LVAD) insertion is
associated with significant mortality and morbidity. Mechanical support options include right …

Durable continuous-flow left ventricular assist devices (cfLVADs) demonstrate superior
survival, cardiac functional status, and overall quality of life compared to medical therapy …

Aortic regurgitation (AR), mitral regurgitation (MR), and tricuspid regurgitation (TR) after
continuous-flow left ventricular assist device (LVAD) are common and may increase with …

Left ventricular assist devices (LVADs) have been used off-label as long-term support of the
right heart due to the lack of a clinically approved durable right VAD (RVAD). Whilst various …

Background Aortic regurgitation (AR) occurs commonly in patients with continuous-flow left
ventricular assist devices (LVAD). No gold standard is available to assess AR severity in this …

We evaluated mean, peak, and instantaneous pressure gradients across the outflow conduit
in a pulsatile mock circulation loop which incorporated Heartware HVADs for left ventricular …