Alcohol consumption is a predominant etiological factor in the pathogenesis of chronic liver
diseases, resulting in fatty liver, alcoholic hepatitis, fibrosis/cirrhosis, and hepatocellular …

Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. The
spectrum of disease ranges from fatty liver to hepatic inflammation, necrosis, progressive …

With easy-to-read, in-depth descriptions of disease, disease etiology, and disease
processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th …

Autophagy is a highly conserved intracellular catabolic pathway that degrades cellular long-
lived proteins and organelles. Autophagy is normally activated in response to nutrient …

Alcohol-related liver disease (ALD) and drug-induced liver injury (DILI) are common causes
of severe liver disease, and successful treatments are lacking. Autophagy plays a protective …

Increasing evidence has demonstrated that dihydromyricetin (DMY) contains highly effective
antioxidative, anti-inflammatory, anti-microbial and anti-diabetic properties. Nevertheless …

This review describes the influence of ethanol consumption on hepatic lipophagy, a
selective form of autophagy during which fat-storing organelles known as lipid droplets …

BACKGROUND/AIMS: Alcoholic liver disease (ALD) is one of the leading causes of cirrhosis
and yet efficient therapeutic strategies are lacking. Polyenephosphatidylcholine (PPC), a …

The majority of ethanol metabolism occurs in the liver. Consequently, this organ sustains the
greatest damage from ethanol abuse. Ethanol consumption disturbs the delicate balance of …

Alcoholic liver disease (ALD) is a common chronic redox disease caused by increased
alcohol consumption. Abstinence is a major challenge for people with alcohol dependence …