Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Importance Worldwide, the burden of heart failure has increased to an estimated 23 million
people, and approximately 50% of cases are HF with reduced ejection fraction (HFrEF) …

Congestion is a cardinal sign of heart failure (HF). In the past, it was seen as a
homogeneous epiphenomenon that identified patients with advanced HF. However, current …

Early telemonitoring of weights and symptoms did not decrease heart failure hospitalizations
but helped identify steps toward effective monitoring programs. A signal that is accurate and …

ABSTRACT Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Background Inhibition of the sodium-glucose cotransporter-2 (SGLT2i) improves outcomes
in patients with heart failure (HF) and reduced ejection fraction (HFrEF), but the mechanism …

The cardiac lymphatic network plays a key role in regulation of myocardial extracellular
volume and immune cell homeostasis. In different pathological conditions cardiac …

Background Comprehensive uptitration of neurohormonal blockade targets fundamental
mechanisms underlying development of congestion and may be an additional approach for …

Background: Heart failure (HF) patients commonly experience obstructive sleep apnea
(OSA), which may worsen their condition. We reviewed a diverse range of studies to …

Organ congestion from venous hypertension is an important pathophysiological mechanism
mediating organ injury in several clinical contexts including critical illness, congestive heart …