The high morbidity and mortality rate of ischemic stroke in humans has led to the
development of numerous animal models that replicate human stroke to further understand …

Background Since the introduction of the philosophical tenet “Time is Brain!,” multiple lines
of research have demonstrated that other factors contribute to the degree of ischemic injury …

Stroke, a major cause of disability, disrupts brain function and motor skills. Previous
research has mainly focused on reorganization of the motor system post-stroke, but the …

Background and Purpose—Large vessel occlusion stroke leads to highly variable
hyperacute infarction growth. Our aim was to identify clinical and imaging parameters …

Over decades of research into the treatment of stroke, nearly all attempts to translate
experimental treatments from discovery in cells and rodents to use in humans have failed …

BACKGROUND AND PURPOSE: Cerebral infarction evolves at different rates depending on
available blood flow suggesting that treatment time windows vary depending on the degree …

Nonhuman primates are closer to human beings than rodents in genetics, neuroanatomy,
physiology and immunology. Nonhuman primates are therefore considered an ideal …

Purpose of Review To explore factors associated with infarct progression in the early and
late phase of acute ischemic stroke in patients undergoing endovascular therapy. Recent …

Purpose: To develop a preliminary deep learning model that uses diffusion-weighted
imaging (DWI) images to classify the severity of neurological impairment caused by ischemic …

Identifying novel neuroprotectants that can halt or reverse the neurological effects of stroke
is of interest to both clinicians and scientists. We and others previously showed the pre …