Diabetes mellitus, energy metabolism, and COVID-19

C Conte, E Cipponeri, M Roden - Endocrine Reviews, 2024 - academic.oup.com
Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Monocytic HLA-DR expression in immune responses of acute pancreatitis and COVID-19

S Liu, W Luo, P Szatmary, X Zhang, JW Lin… - International Journal of …, 2023 - mdpi.com
Acute pancreatitis is a common gastrointestinal disease with increasing incidence
worldwide. COVID-19 is a potentially life-threatening contagious disease spread throughout …

Mapping the Lipid Signatures in COVID-19 Infection: Diagnostic and Therapeutic Solutions

A Dasgupta, S Gangai, R Narayan… - Journal of Medicinal …, 2023 - ACS Publications
The COVID-19 pandemic ignited research centered around the identification of robust
biomarkers and therapeutic targets. SARS-CoV-2, the virus responsible, hijacks the …

Lipid compartments and lipid metabolism as therapeutic targets against coronavirus

D Cesar-Silva, FS Pereira-Dutra, ALM Giannini… - Frontiers in …, 2023 - frontiersin.org
Lipids perform a series of cellular functions, establishing cell and organelles' boundaries,
organizing signaling platforms, and creating compartments where specific reactions occur …

Identification and characterization of a marine bacterium extract from Mameliella sp. M20D2D8 with antiviral effects against influenza A and B viruses

HJ Kim, JG Park, KS Moon, SB Jung, YM Kwon… - Archives of …, 2024 - Springer
Despite significant improvements in vaccines and chemotherapeutic drugs, pathogenic RNA
viruses continue to have a profound impact on the global economy and pose a serious …

Lipid droplets in pathogen infection and host immunity

Y Tan, Y Jin, J Zhou, Y Yang - Acta Pharmacologica Sinica, 2024 - nature.com
As the hub of cellular lipid metabolism, lipid droplets (LDs) have been linked to a variety of
biological processes. During pathogen infection, the biogenesis, composition, and functions …

Rewiring of the host cell metabolome and lipidome during lytic gammaherpesvirus infection is essential for infectious-virus production

SA Clark, A Vazquez, K Furiya… - Journal of …, 2023 - Am Soc Microbiol
Oncogenic virus infections are estimated to cause~ 15% of all cancers. Two prevalent
human oncogenic viruses are members of the gammaherpesvirus family: Epstein-Barr virus …

Liposome-Mediated Anti-Viral Drug Delivery Across Blood–Brain Barrier: Can Lipid Droplet Target Be Game Changers?

S Mondal, S Ghosh - Cellular and Molecular Neurobiology, 2024 - Springer
Lipid droplets (LDs) are subcellular organelles secreted from the endoplasmic reticulum
(ER) that play a major role in lipid homeostasis. Recent research elucidates additional roles …

[HTML][HTML] Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against …

WS Kim, SH Jeong, KW Shin, HJ Lee, JY Park… - International …, 2023 - Elsevier
The therapeutic benefits of curcuminoids in various diseases have been extensively
reported. However, little is known regarding their preventive effects on extensive …

[HTML][HTML] Porcine enteric alphacoronavirus infection increases lipid droplet accumulation to facilitate the virus replication

Q Gao, Y Feng, T Gong, D Wu, X Zheng, Y Luo… - Journal of Integrative …, 2024 - Elsevier
Coronaviruses are widely transmissible between humans and animals, causing diseases of
varying severity. Porcine enteric alphacoronavirus (PEAV) is a newly-discovered pathogenic …