Inertial microfluidics: current status, challenges, and future opportunities

N Xiang, Z Ni - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics uses the hydrodynamic effects induced at finite Reynolds numbers to
achieve passive manipulation of particles, cells, or fluids and offers the advantages of high …

Recent microfluidic advances in submicron to nanoparticle manipulation and separation

S Hettiarachchi, H Cha, L Ouyang, A Mudugamuwa… - Lab on a Chip, 2023 - pubs.rsc.org
Manipulation and separation of submicron and nanoparticles are indispensable in many
chemical, biological, medical, and environmental applications. Conventional technologies …

Advances in technical assessment of spiral inertial microfluidic devices toward bioparticle separation and profiling: A critical review

M Bagi, F Amjad, SM Ghoreishian… - BioChip Journal, 2024 - Springer
Separation of micro-and nano-sized bioparticles is essential for efficient diagnostics,
chemical and biological analyses, drug development, food and chemical processing, and …

Multi-dimensional-double-spiral (MDDS) inertial microfluidic platform for sperm isolation directly from the raw semen sample

H Jeon, C Cremers, D Le, J Abell, J Han - Scientific reports, 2022 - nature.com
Here, we propose a fully-automated platform using a spiral inertial microfluidic device for
standardized semen preparation that can process patient-derived semen samples with …

[HTML][HTML] 3D-stacked multistage inertial microfluidic chip for high-throughput enrichment of circulating tumor cells

X Xu, X Huang, J Sun, J Chen, G Wu, Y Yao… - Cyborg and Bionic …, 2022 - spj.science.org
Whether for cancer diagnosis or single-cell analysis, it remains a major challenge to isolate
the target sample cells from a large background cell for high-efficiency downstream …

[HTML][HTML] A review on inertial microfluidic fabrication methods

Z Akbari, MA Raoufi, S Mirjalali, B Aghajanloo - Biomicrofluidics, 2023 - pubs.aip.org
In recent decades, there has been significant interest in inertial microfluidics due to its high
throughput, ease of fabrication, and no need for external forces. The focusing efficiency of …

Removal of cell clusters from CHO suspension cultures based on large-particle trapping effect in spiral inertial microfluidics

T Kwon, H Jeon, JFP Hamel, J Han - Separation and Purification …, 2024 - Elsevier
Suspension cultures of Chinese hamster ovary (CHO) cells are extensively employed in
biopharmaceutical production. During cultivation, CHO cell clusters often form due to cell …

Rapid and label-Free classification of blood leukocytes for immune state monitoring

H Jeon, M Wei, X Huang, J Yao, W Han… - Analytical …, 2022 - ACS Publications
A fully automated and label-free sample-to-answer white blood cell (WBC) cytometry
platform for rapid immune state monitoring is demonstrated. The platform integrates (1) a …

Numerical simulation of inertial microfluidics: a review

R Shi - Engineering Applications of Computational Fluid …, 2023 - Taylor & Francis
Since the proposal of inertial microfluidics in 2007, it has been widely used for particle
focusing and separation with superior performances. The particle migration behaviour in …

Recent progress and perspectives on neural chip platforms integrating PDMS-based microfluidic devices and microelectrode arrays

S Xu, Y Liu, Y Yang, K Zhang, W Liang, Z Xu, Y Wu… - Micromachines, 2023 - mdpi.com
Recent years have witnessed a spurt of progress in the application of the encoding and
decoding of neural activities to drug screening, diseases diagnosis, and brain–computer …