[HTML][HTML] Cell death due to electroporation–a review

TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

[HTML][HTML] A review on cell damage, viability, and functionality during 3D bioprinting

HQ Xu, JC Liu, ZY Zhang, CX Xu - Military Medical Research, 2022 - Springer
Abstract Three-dimensional (3D) bioprinting fabricates 3D functional tissues/organs by
accurately depositing the bioink composed of the biological materials and living cells. Even …

[HTML][HTML] Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

J Yang, A Griffin, Z Qiang, J Ren - Signal transduction and targeted …, 2022 - nature.com
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …

WRN helicase is a synthetic lethal target in microsatellite unstable cancers

EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi… - Nature, 2019 - nature.com
Synthetic lethality—an interaction between two genetic events through which the co-
occurrence of these two genetic events leads to cell death, but each event alone does not …

[HTML][HTML] Roles of heat shock proteins in apoptosis, oxidative stress, human inflammatory diseases, and cancer

PC Ikwegbue, P Masamba, BE Oyinloye, AP Kappo - Pharmaceuticals, 2017 - mdpi.com
Heat shock proteins (HSPs) play cytoprotective activities under pathological conditions
through the initiation of protein folding, repair, refolding of misfolded peptides, and possible …

Non-histone protein methylation as a regulator of cellular signalling and function

KK Biggar, SSC Li - Nature reviews Molecular cell biology, 2015 - nature.com
Abstract Methylation of Lys and Arg residues on non-histone proteins has emerged as a
prevalent post-translational modification and as an important regulator of cellular signal …

Melanocytic nevi and melanoma: unraveling a complex relationship

WE Damsky, M Bosenberg - Oncogene, 2017 - nature.com
Approximately 33% of melanomas are derived directly from benign, melanocytic nevi.
Despite this, the vast majority of melanocytic nevi, which typically form as a result of BRAF …

[HTML][HTML] Crosstalk between PTEN/PI3K/Akt signalling and DNA damage in the oocyte: implications for primordial follicle activation, oocyte quality and ageing

M Maidarti, RA Anderson, EE Telfer - Cells, 2020 - mdpi.com
The preservation of genome integrity in the mammalian female germline from primordial
follicle arrest to activation of growth to oocyte maturation is fundamental to ensure …

Cell death pathways of particulate matter toxicity

MS Peixoto, MF de Oliveira Galvão, SRB de Medeiros - Chemosphere, 2017 - Elsevier
Humans are exposed to various complex mixtures of particulate matter (PM) from different
sources. Long-term exposure to high levels of these particulates has been linked to a …

[HTML][HTML] DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity

JR Kok, NM Palminha, C Dos Santos Souza… - Cellular and Molecular …, 2021 - Springer
Increasing evidence supports the involvement of DNA damage in several
neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Elevated levels …