Molecular and imaging biomarkers in Alzheimer's disease: a focus on recent insights
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly, affecting millions of people worldwide and clinically characterized by a progressive …
elderly, affecting millions of people worldwide and clinically characterized by a progressive …
Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders
E Maffioletti, D Tardito, M Gennarelli… - Frontiers in cellular …, 2014 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNAs (20–22 nucleotides) playing a major role
in post-transcriptional regulation of gene expression. miRNAs are predicted to regulate more …
in post-transcriptional regulation of gene expression. miRNAs are predicted to regulate more …
Epigenetic peripheral biomarkers for early diagnosis of Alzheimer's disease
C Villa, A Stoccoro - Genes, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and represents the
leading cause of cognitive impairment and dementia in older individuals throughout the …
leading cause of cognitive impairment and dementia in older individuals throughout the …
[HTML][HTML] Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1
QS Li, L De Muynck - Brain, Behavior, & Immunity-Health, 2021 - Elsevier
Background Alzheimer's disease (AD) is associated with abnormal tau and amyloid-β
accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and …
accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and …
microRNAs in nociceptive circuits as predictors of future clinical applications
Neuro-immune alterations in the peripheral and central nervous system play a role in the
pathophysiology of chronic pain, and non-coding RNAs (ncRNAs)–and microRNAs …
pathophysiology of chronic pain, and non-coding RNAs (ncRNAs)–and microRNAs …
The potential of microRNAs as biofluid markers of neurodegenerative diseases–a systematic review
PB Danborg, AH Simonsen, G Waldemar… - Biomarkers, 2014 - Taylor & Francis
MicroRNAs (miRNA) are biological molecules transcribed from non-protein coding regions
of the genome, participating in regulating cellular processes. MiRNAs in biofluids may …
of the genome, participating in regulating cellular processes. MiRNAs in biofluids may …
Muscle involvement in amyotrophic lateral sclerosis: understanding the pathogenesis and advancing therapeutics
Amyotrophic lateral sclerosis (ALS) is a fatal condition characterized by the selective loss of
motor neurons in the motor cortex, brainstem, and spinal cord. Muscle involvement, muscle …
motor neurons in the motor cortex, brainstem, and spinal cord. Muscle involvement, muscle …
Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes
Specific spontaneous heritable neurodegenerative diseases have been associated with
lower serum and cerebrospinal fluid α-tocopherol (α-TOH) concentrations. Equine …
lower serum and cerebrospinal fluid α-tocopherol (α-TOH) concentrations. Equine …
Influence of DUX4 Expression in Facioscapulohumeral Muscular Dystrophy and Possible Treatments
Facioscapulohumeral muscular dystrophy (FSHD) represents the third most common form of
muscular dystrophy and is characterized by muscle weakness and atrophy. FSHD is caused …
muscular dystrophy and is characterized by muscle weakness and atrophy. FSHD is caused …
Gene expression profiles of M1 and M2 microglia characterized by comparative analysis of public datasets
J Satoh - Clinical and Experimental Neuroimmunology, 2018 - Wiley Online Library
Objective Microglia, immunocompetent cells in the central nervous system, adopt two distinct
activation phenotypes, composed of a pro‐inflammatory and neurotoxic “classical” activation …
activation phenotypes, composed of a pro‐inflammatory and neurotoxic “classical” activation …