Fluid transport in the brain

MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

Current concepts in intracranial interstitial fluid transport and the glymphatic system: part II—imaging techniques and clinical applications

JM Klostranec, D Vucevic, KD Bhatia, HGJ Kortman… - Radiology, 2021 - pubs.rsna.org
The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

Glymphatic dysfunction in patients with ischemic stroke

CH Toh, TY Siow - Frontiers in aging neuroscience, 2021 - frontiersin.org
Objectives: Rodent experiments have provided some insight into the changes of glymphatic
function in ischemic stroke. The diffusion tensor image analysis along the perivascular …

Functional analysis of the human perivascular subarachnoid space

PK Eide, G Ringstad - Nature Communications, 2024 - nature.com
The human subarachnoid space harbors the cerebrospinal fluid, which flows within a
landscape of blood vessels and trabeculae. Functional implications of subarachnoid space …

Perivascular spaces, glymphatic system and MR

L Yu, X Hu, H Li, Y Zhao - Frontiers in Neurology, 2022 - frontiersin.org
The importance of the perivascular space (PVS) as one of the imaging markers of cerebral
small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The …

The glymphatic system: a review of the challenges in visualizing its structure and function with MR imaging

S Naganawa, T Taoka - Magnetic Resonance in Medical Sciences, 2022 - jstage.jst.go.jp
The central nervous system (CNS) was previously thought to be the only organ system
lacking lymphatic vessels to remove waste products from the interstitial space. Recently …

Noninvasive magnetic resonance imaging measures of glymphatic system activity

K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

Glymphatic cerebrospinal fluid and solute transport quantified by MRI and PET imaging

H Benveniste, H Lee, B Ozturk, X Chen, S Koundal… - Neuroscience, 2021 - Elsevier
Over the past decade there has been an enormous progress in our understanding of fluid
and solute transport in the central nervous system (CNS). This is due to a number of factors …

The glymphatic system in humans: investigations with magnetic resonance imaging

S Naganawa, T Taoka, R Ito… - Investigative …, 2024 - journals.lww.com
The concept of the glymphatic system was proposed more than a decade ago as a
mechanism for interstitial fluid flow and waste removal in the central nervous system. The …

Molecular trans-dural efflux to skull bone marrow in humans with CSF disorders

G Ringstad, PK Eide - Brain, 2022 - academic.oup.com
Dural sinuses were recently identified as a hub for peripheral immune surveillance of brain-
derived antigens cleared through CSF. However, animal studies have also indicated that …