[HTML][HTML] The bidirectional relationship of depression and inflammation: double trouble

E Beurel, M Toups, CB Nemeroff - Neuron, 2020 - cell.com
Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …

Stress, the autonomic nervous system, and the immune-kynurenine pathway in the etiology of depression

E Won, YK Kim - Current neuropharmacology, 2016 - ingentaconnect.com
The autonomic nervous system is one of the major neural pathways activated by stress. In
situations that are often associated with chronic stress, such as major depressive disorder …

The role of IL-17 in CNS diseases

A Waisman, J Hauptmann, T Regen - Acta neuropathologica, 2015 - Springer
Cytokines of the IL-17 family are uniquely placed on the border between immune cells and
tissue. Although IL-17 was originally found to induce the activation and mobilization of …

Th17 cells in depression

E Beurel, JA Lowell - Brain, behavior, and immunity, 2018 - Elsevier
Abstract T helper 17 (Th17) cells have recently been implicated in depression, which adds to
the list of several other diseases of the central nervous system (CNS) that are already known …

Targeting the adaptive immune system in depression: focus on T helper 17 cells

E Beurel, EM Medina-Rodriguez, RS Jope - Pharmacological reviews, 2022 - ASPET
There is a vital need to understand mechanisms contributing to susceptibility to depression
to improve treatments for the 11% of Americans who currently suffer from this debilitating …

[HTML][HTML] Elevated IL-17 and TGF-β serum levels: a positive correlation between T-helper 17 cell-related pro-inflammatory responses with major depressive disorder

MH Davami, R Baharlou, AA Vasmehjani… - Basic and clinical …, 2016 - ncbi.nlm.nih.gov
Methods: Blood samples were collected from 41 patients with major depressive disorder and
40 healthy age-matched controls with no history of malignancies or autoimmune disorders …

[HTML][HTML] Depression and obesity in patients with psoriasis and psoriatic arthritis: is IL-17-mediated immune dysregulation the connecting link?

E Zafiriou, AI Daponte, V Siokas, C Tsigalou… - Frontiers in …, 2021 - frontiersin.org
Patients with psoriasis are frequently obese and experience anxiety or suffer from
depressive disorders. The immunopathogenesis of psoriasis and indeed psoriatic arthritis is …

Fluoxetine treatment affects the inflammatory response and microglial function according to the quality of the living environment

S Alboni, S Poggini, S Garofalo, G Milior… - Brain, behavior, and …, 2016 - Elsevier
It has been hypothesized that selective serotonin reuptake inhibitors (SSRIs), the most
common treatment for major depression, affect mood through changes in immune function …

Abnormal protein and mRNA expression of inflammatory cytokines in the prefrontal cortex of depressed individuals who died by suicide

GN Pandey, HS Rizavi, H Zhang, R Bhaumik… - Journal of psychiatry and …, 2018 - jpn.ca
Background: Depression and stress are major risk factors for suicidal behaviour, and some
studies show abnormalities of proinflammatory cytokines in the serum and cerebrospinal …

Brain-immune crosstalk in the treatment of major depressive disorder

I Branchi, S Poggini, L Capuron, F Benedetti… - European …, 2021 - Elsevier
A growing number of studies are pointing out the need for a conceptual shift from a brain-
centered to a body-inclusive approach in mental health research. In this perspective, the link …