Raman spectroscopy: techniques and applications in the life sciences
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …
Single cell optical imaging and spectroscopy
AS Stender, K Marchuk, C Liu, S Sander… - Chemical …, 2013 - ACS Publications
In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …
made using a microscope, including compartment-like structures in cork samples that he …
Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells
Single-cell sequencing technologies have revealed an unexpectedly broad repertoire of
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
cells required to mediate complex functions in multicellular organisms. Despite the multiple …
A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis elegans Using Label and Label-Free Methods
The nematode Caenorhabditis elegans has been employed as a model organism to study
human obesity due to the conservation of the pathways that regulate energy metabolism. To …
human obesity due to the conservation of the pathways that regulate energy metabolism. To …
Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy
JP Pezacki, JA Blake, DC Danielson… - Nature chemical …, 2011 - nature.com
Cellular biomolecules contain unique molecular vibrations that can be visualized by
coherent anti-Stokes Raman scattering (CARS) microscopy without the need for labels. Here …
coherent anti-Stokes Raman scattering (CARS) microscopy without the need for labels. Here …
Minireview: PPARγ as the target of obesogens
A Janesick, B Blumberg - The Journal of steroid biochemistry and …, 2011 - Elsevier
The peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of
adipogenesis and is medically important for its connections to obesity and the treatment of …
adipogenesis and is medically important for its connections to obesity and the treatment of …
Multimodal nonlinear optical microscopy
Because each nonlinear optical (NLO) imaging modality is sensitive to specific molecules or
structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies …
structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies …
[HTML][HTML] Plasma membranes as heat stress sensors: from lipid-controlled molecular switches to therapeutic applications
The classic heat shock (stress) response (HSR) was originally attributed to protein
denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances …
denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances …
Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy
Despite the ubiquitous roles of lipids in biology, the detection of lipids has relied on invasive
techniques, population measurements, or nonspecific labeling. Such difficulties can be …
techniques, population measurements, or nonspecific labeling. Such difficulties can be …
Curcumin inhibits adipocyte differentiation through modulation of mitotic clonal expansion
Adipocyte differentiation is a key process in determining the number of mature adipocytes in
the development of obesity. Here, we examined the function of curcumin, a dietary …
the development of obesity. Here, we examined the function of curcumin, a dietary …