How Does Airway Surface Liquid Composition Vary in Different Pulmonary Diseases, and How Can We Use This Knowledge to Model Microbial Infections?
D Walsh, J Bevan, F Harrison - Microorganisms, 2024 - mdpi.com
Growth environment greatly alters many facets of pathogen physiology, including
pathogenesis and antimicrobial tolerance. The importance of host-mimicking environments …
pathogenesis and antimicrobial tolerance. The importance of host-mimicking environments …
In vitro analysis of Pseudomonas aeruginosa virulence using conditions that mimic the environment at specific infection sites
JA Colmer-Hamood, N Dzvova, C Kruczek… - Progress in molecular …, 2016 - Elsevier
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes chronic
lung infection in patients with cystic fibrosis (CF) and acute systemic infections in severely …
lung infection in patients with cystic fibrosis (CF) and acute systemic infections in severely …
Formation of Pseudomonas aeruginosa Biofilms in Full-thickness Scald Burn Wounds in Rats
Abstract Using Sprague-Dawley rats (350–450 g; n= 61) and the recently updated Walker-
Mason rat scald burn model, we demonstrated that Pseudomonas aeruginosa readily …
Mason rat scald burn model, we demonstrated that Pseudomonas aeruginosa readily …
Glutathione-disrupted biofilms of clinical Pseudomonas aeruginosa strains exhibit an enhanced antibiotic effect and a novel biofilm transcriptome
Pseudomonas aeruginosa infections result in high morbidity and mortality rates for
individuals with cystic fibrosis (CF), with premature death often occurring. These infections …
individuals with cystic fibrosis (CF), with premature death often occurring. These infections …
[HTML][HTML] Development of liquid culture media mimicking the conditions of sinuses and lungs in cystic fibrosis and health
The respiratory tract is a compartmentalised and heterogenous environment. The
nasopharynx and sinuses of the upper airways have distinct properties from the lungs and …
nasopharynx and sinuses of the upper airways have distinct properties from the lungs and …
Surviving the host: Microbial metabolic genes required for growth of Pseudomonas aeruginosa in physiologically-relevant conditions
Pseudomonas aeruginosa, like other pathogens, adapts to the limiting nutritional
environment of the host by altering patterns of gene expression and utilizing alternative …
environment of the host by altering patterns of gene expression and utilizing alternative …
Cerebrospinal fluid (CSF) augments metabolism and virulence expression factors in Acinetobacter baumannii
J Martinez, C Razo-Gutierrez, C Le, R Courville… - Scientific Reports, 2021 - nature.com
In a recent report by the Centers for Disease Control and Prevention (CDC), multidrug
resistant (MDR) Acinetobacter baumannii is a pathogen described as an “urgent threat.” …
resistant (MDR) Acinetobacter baumannii is a pathogen described as an “urgent threat.” …
Development of Pseudomonas aeruginosa Biofilms in Partial-Thickness Burn Wounds Using a Sprague-Dawley Rat Model
KS Brandenburg, AJ Weaver Jr, L Qian… - Journal of Burn Care …, 2019 - academic.oup.com
We used a modified Walker–Mason scald burn rat model to demonstrate that Pseudomonas
aeruginosa, a common opportunistic pathogen in the burn ward and notable biofilm former …
aeruginosa, a common opportunistic pathogen in the burn ward and notable biofilm former …
The Iron Content of Human Serum Albumin Modulates the Susceptibility of Acinetobacter baumannii to Cefiderocol
J Escalante, B Nishimura, MR Tuttobene, T Subils… - Biomedicines, 2023 - mdpi.com
The mortality rates of patients infected with Acinetobacter baumannii who were treated with
cefiderocol (CFDC) were not as favorable as those receiving the best available treatment for …
cefiderocol (CFDC) were not as favorable as those receiving the best available treatment for …
During bacteremia, Pseudomonas aeruginosa PAO1 adapts by altering the expression of numerous virulence genes including those involved in quorum sensing
KL Beasley, SA Cristy, MM Elmassry, N Dzvova… - PloS one, 2020 - journals.plos.org
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that produces
numerous virulence factors and causes serious infections in trauma patients and patients …
numerous virulence factors and causes serious infections in trauma patients and patients …