Pain, fatigue, and physical activity are major determinants of life quality in rheumatoid
arthritis (RA). Janus kinase (JAK) inhibitors have emerged as effective medications in RA …

Introduction Various approaches have been suggested to identify acute kidney injury (AKI)
early and to initiate kidney-protective measures in patients at risk or with AKI. The objective …

Aims Optimal duration of dual antiplatelet therapy (DAPT) in patients with concomitant
indication to oral anticoagulation (OAC) is still debated. Methods and results A systematic …

Meta-analysis may increase the risk of random errors. Trial sequential analysis (TSA) has
been developed to adjust for these random errors. We conducted TSA on the efficacy and …

Background Patch angioplasty in conventional carotid endarterectomy is suggested to
reduce the risk of restenosis and recurrent ipsilateral stroke compared with primary closure …

Aims To test the efficacy of 'MiQuit', a tailored, self‐help, text message stop smoking
programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in …

Objective Targeted temperature management (TTM) with therapeutic hypothermia (TH) has
been used to improve neurological outcomes in patients after cardiac arrest; however …

Background Systematic reviews and data synthesis of randomised clinical trials play a
crucial role in clinical practice, research, and health policy. Trial sequential analysis can be …

Background/Objectives: Prophylactic antibiotics (PAB) are being still widely used for
treatment of acute pancreatitis (AP) despite trials showing no firm evidence of efficacy. We …

Parenting programs are the most common intervention for preventing the lethal form of child
maltreatment, abusive head trauma (AHT). However, certain results of the effects of these …