Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

The article is mainly devoted to such representatives of gut microbiota as lactic acid bacteria
and bifidobacteria, with minor accent on less frequently used or new probiotic …

Metabolic engineering of microorganisms to produce desirable products on an industrial
scale can result in unbalanced cellular metabolic networks that reduce productivity and …

Control of native enzyme levels is important when optimizing strains for overproduction of
heterologous compounds. However, for many central metabolic enzymes, static knockdown …

Saccharides have recently attracted considerable attention because of their biological
functions and potential applications in the pharmaceutical, cosmetic and food industries …

Highlights●scyllo-Inositol and D-chiro-inositol are known for their health-promoting
effects.●Inexpensive mass production of these inositols is awaited.●Bacillus subtilis and …

Preclinical development of scyllo-inositol for the treatment of Alzheimer's disease (AD) has
been investigated in both in vitro and in vivo models with positive results. scyllo-Inositol …

The compound inositol has many important applications in various fields. However, no
information can be obtained on the biosynthesis of inositol by lactic acid bacteria (LAB) so …

Scyllo-inositol has been identified as a potential drug for the treatment of Alzheimer's
disease. Therefore, cost-efficient processes for the production of this compound are …

Bacillus subtilis has been studied for more than half a century, ever since the dawn of
molecular biology, as a representative Gram-positive bacterium and cell factory. Two …