GSH plays an important role during the onset and progression of neuropsychiatric and
neurodegenerative diseases. GSH redox imbalance may be a primary cause of these brain …

We review the transport, synthesis and catabolism of glutathione in the brain as well as its
compartmentation and biochemistry in different brain cells. The major reactions involving …

Mood and psychotic syndromes most often emerge during adolescence and young
adulthood, a period characterised by major physical and social change. Consequently, the …

Background Glutathione [GSH] is a major intracellular antioxidant that disposes peroxides
and protects neurons and glial cells from oxidative stress. In both schizophrenia and bipolar …

Background Bipolar disorder (BD) is associated with chronic low-grade inflammation,
several medical comorbidities and a decreased life expectancy. Metabolic-inflammatory …

Background Alcohol‐induced blackouts, or memory loss for all or portions of events that
occurred during a drinking episode, are reported by approximately 50% of drinkers and are …

Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …

Binge drinking has significant effects on memory, particularly with regards to the transfer of
information to long-term storage. Partial or complete blocking of memory formation is known …

Abstract Introduction N-Acetylcysteine (NAC) may have efficacy in treating tobacco use
disorder (TUD) by reducing craving and smoking reward. This study examines whether …

Aims Bipolar type I disorder (BD) is characterized by severe mood swings and occurs in
about 1% of the population. The mechanisms underlying the disorder remain unknown. Prior …