Endometriosis and autoimmunity: Can autoantibodies be used as a non-invasive early diagnostic tool?

H Greenbaum, DH Decter, VH Eisenberg - Autoimmunity reviews, 2021 - Elsevier
This review aims to assess the current and past literature for efficacious non-invasive
diagnostic markers for earlier detection of endometriosis. We briefly discussed the …

Nuclear factor-κB (NF-κB): an unsuspected major culprit in the pathogenesis of endometriosis that is still at large?

SW Guo - Gynecologic and obstetric investigation, 2007 - karger.com
Endometriosis, defined as the ectopic presence of endometrial glandular and stromal cells
outside the uterine cavity, is a common benign gynecological disorder with an enigmatic …

[HTML][HTML] The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in …

C Pellegrini, I Gori, C Achtari, D Hornung… - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To analyze the expression of estrogen receptors α and β as well as their target
genes implicated in proliferation, c-myc, cyclin D1, and GREB1, in the endometrium of …

Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis

K Proestling, P Birner, S Gamperl, N Nirtl… - Reproductive Biology …, 2015 - Springer
Background Epithelial to mesenchymal transition (EMT) is a process in which epithelial cells
lose polarity and cell-to-cell contacts and acquire the migratory and invasive abilities of …

Aberrant expression of apoptosis-related molecules in endometriosis: a possible mechanism underlying the pathogenesis of endometriosis

K Nasu, M Nishida, Y Kawano, A Tsuno… - Reproductive …, 2011 - journals.sagepub.com
Endometriosis, a disease affecting 3% to 10% of women of reproductive age, is
characterized by the ectopic growth of endometrial tissue under the influence of estrogen. It …

Molecular mechanisms and biological plausibility underlying the malignant transformation of endometriosis: a critical analysis

P Viganó, E Somigliana, I Chiodo… - Human reproduction …, 2006 - academic.oup.com
Although population-based studies have unequivocally reported an increased risk of
ovarian cancer in women with endometriosis, the biological evidence supporting the idea of …

[HTML][HTML] Endometriosis and ovarian cancer: potential benefits and harms of screening and risk-reducing surgery

SW Guo - Fertility and sterility, 2015 - Elsevier
Although endometriosis is well recognized as a benign gynecologic condition, its
association with ovarian cancer (OVCA) has frequently been reported. Review articles on …

An investigation of the effects of endometriosis on the proteome of human eutopic endometrium: a heterogeneous tissue with a complex disease

PA Fowler, J Tattum, S Bhattacharya, T Klonisch… - …, 2007 - Wiley Online Library
The pathogenesis of endometriosis includes the proliferation of heterogeneous endometrial
cells and their invasion into ectopic sites within the peritoneal cavity. This may be due to …

Cancer driver mutations in endometriosis: variations on the major theme of fibrogenesis

SW Guo - Reproductive medicine and biology, 2018 - Wiley Online Library
Background One recent study reports cancer driver mutations in deep endometriosis, but its
biological/clinical significance remains unclear. Since the natural history of endometriosis is …

WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells

B Gurates, S Sebastian, S Yang, J Zhou… - The Journal of …, 2002 - academic.oup.com
The orphan nuclear receptor steroidogenic factor-1 (SF-1) induces the expression of
Müllerian inhibiting substance (MIS) and many steroidogenic genes, including aromatase …