[HTML][HTML] An observational study on factors associated with ICU mortality in Covid-19 patients and critical review of the literature

A Lavrentieva, E Kaimakamis, V Voutsas, M Bitzani - Scientific Reports, 2023 - nature.com
The novel pandemic caused by SARS-CoV-2 has been associated with increased burden
on healthcare system. Recognizing the variables that independently predict death in COVID …

[HTML][HTML] Inflammasome activation in infected macrophages drives COVID-19 pathology

E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao… - Nature, 2022 - nature.com
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine
production, viral RNA and a sustained interferon (IFN) response, all of which are …

[HTML][HTML] A glucose meter interface for point-of-care gene circuit-based diagnostics

E Amalfitano, M Karlikow, M Norouzi, K Jaenes… - Nature …, 2021 - nature.com
Recent advances in cell-free synthetic biology have given rise to gene circuit-based sensors
with the potential to provide decentralized and low-cost molecular diagnostics. However, it …

[HTML][HTML] Ivermectin: a controversial focal point during the COVID-19 pandemic

M Castillejos-López, LM Torres-Espíndola… - Life, 2022 - mdpi.com
The SARS-CoV-2 pandemic has confirmed the apocalyptic predictions that virologists have
been making for several decades. The challenge the world is facing is that of trying to find a …

[HTML][HTML] Differential functional responses of neutrophil subsets in severe COVID-19 patients

KR McLeish, R Shrestha, A Vashishta… - Frontiers in …, 2022 - frontiersin.org
Neutrophils play a significant role in determining disease severity following SARS-CoV-2
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …

The experiences of patients, family caregivers, healthcare providers, and health service leaders with compassionate care following hospitalization with COVID-19: a …

R Simpson, Z Szigeti, CL Sheppard… - Disability and …, 2023 - Taylor & Francis
Purpose This study explored the experiences of patients, caregivers, healthcare providers,
and health service leaders of compassion in the care of people hospitalized with COVID-19 …

[PDF][PDF] Mitochondrial dysfunction, lipids metabolism, and amino acid biosynthesis are key pathways for COVID-19 recovery

A Sánchez, G García-Pardo, F Gómez-Bertomeu… - Iscience, 2023 - cell.com
The metabolic alterations caused by SARS-CoV-2 infection reflect disease progression. To
analyze molecules involved in these metabolic changes, a multiomics study was performed …

Intensive care‐related cognitive impairment: a biopsychosocial overview

JL Tingey, NA Dasher, AE Bunnell, AJ Starosta - PM&R, 2022 - Wiley Online Library
Advancements in critical care medicine have improved survival rates for patients
experiencing critical illness in intensive care units (ICUs). Although mortality has declined …

[HTML][HTML] Pleiotropic Functions of Nitric Oxide Produced by Ascorbate for the Prevention and Mitigation of COVID-19: A Revaluation of Pauling's Vitamin C Therapy

H Yamasaki, H Imai, A Tanaka, JM Otaki - Microorganisms, 2023 - mdpi.com
Linus Pauling, who was awarded the Nobel Prize in Chemistry, suggested that a high dose
of vitamin C (l-ascorbic acid) might work as a prevention or treatment for the common cold …

[HTML][HTML] CT-based radiogenomics framework for COVID-19 using ACE2 imaging representations

T Xia, X Fu, M Fulham, Y Wang, D Feng, J Kim - Journal of Digital Imaging, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory
Syndrome Coronavirus 2 which enters the body via the angiotensin-converting enzyme 2 …