Sarcopenic obesity and diabetes are two increasing health problems worldwide, which both
share many common risk factors, such as aging, and general obesity. The pathogenesis of …

Osteoporosis, a condition of skeletal decline that undermines quality of life, is treated with
pharmacological interventions that are associated with poor adherence and adverse effects …

The presence of adipocytes in mammalian bone marrow (BM) has been recognized
histologically for decades, yet, until recently, these cells have received little attention from …

Aging entails the inevitable loss of the structural and functional integrity of cells and tissues
during the lifetime. It is a highly hormone-dependent process; although, the exact …

Although the adipose tissue (AT) is a central metabolic organ in the regulation of whole-
body energy homeostasis, it is also an important endocrine and immunological organ. As an …

The recent description of adipose tissues of various phenotypes within an osteoarthritic joint
allows us to evoke their direct involvement in the initiation and progression of the …

Background Presence of clonal hematopoiesis of indeterminate potential (CHIP) is
associated with a higher risk of atherosclerotic cardiovascular disease, cancer, and …

Haematopoietic stem cells (HSCs) reside in the bone marrow and are supported by the
specialised microenvironment, a niche to maintain HSC quiescence. To deal with …

Marrow adipose tissue (MAT) and its relevance to skeletal health during caloric restriction
(CR) is unknown: It remains unclear whether exercise, which is anabolic to bone in a calorie …

Introduction The incidence of obesity, a condition characterized by systemic chronic
inflammation, has reached pandemic proportions and is a poor prognostic factor in many …